Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.

Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.

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http://www.wikidata.org/entity/Q43245922
Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity ‡Optimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin LMining a cathepsin inhibitor library for new antiparasitic drug leadsExpression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasiteBlocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132Using specificity to strategically target proteases.Antimalarial activity of azadipeptide nitrilesCentenary celebrations article: Cysteine proteases of human malaria parasites.Inhibition of Plasmodium falciparum oocyst production by membrane-permeant cysteine protease inhibitor E64d.Structure-function of falcipains: malarial cysteine proteases.Molecular recognition in chemical and biological systems.Plasmodium food vacuole plasmepsins are activated by falcipains.An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.Dynamical footprint of falcipain-2 catalytic triad in hemoglobin-β-bound state.Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics.Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid.Synthesis of novel benzimidazole acrylonitriles for inhibition of Plasmodium falciparum growth by dual target inhibition.
P2860

Substrate mapping and inhibitor profiling of falcipain-2, falcipain-3 and berghepain-2: implications for peptidase anti-malarial drug discovery.

Item
http://www.wikidata.org/entity/Q43245922
description
2006 nî lūn-bûn
@nan
2006 թվականի հոկտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Substrate mapping and inhibito ...... anti-malarial drug discovery.
@en
Substrate mapping and inhibito ...... anti-malarial drug discovery.
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type
label
Substrate mapping and inhibito ...... anti-malarial drug discovery.
@en
Substrate mapping and inhibito ...... anti-malarial drug discovery.
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prefLabel
Substrate mapping and inhibito ...... anti-malarial drug discovery.
@en
Substrate mapping and inhibito ...... anti-malarial drug discovery.
@nl
P1433
P1476
P2093
P2860
P304
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P356
P407
P433
P478
P577
P5875
P698
P921
P932
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P1433
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Substrate mapping and inhibito ...... anti-malarial drug discovery.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932