The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
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Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cellsRole of DNA repair machinery and p53 in the testicular germ cell cancer: a reviewTumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancerPhase 1B study of amuvatinib in combination with five standard cancer therapies in adults with advanced solid tumors.Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy?The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cellsAn optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.Ribosomal protein S27-like in colorectal cancer: a candidate for predicting prognoses.Against Lung Cancer Cells: To Be, or Not to Be, That Is the ProblemDevelopment of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.Treatment Outcome and Prognostic Molecular Markers of Supratentorial Primitive Neuroectodermal Tumors.Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome.Overexpression of Rad51 Predicts Poor Prognosis in Colorectal Cancer: Our Experience with 54 Patients.Antagonism between curcumin and the topoisomerase II inhibitor etoposide: a study of DNA damage, cell cycle regulation and death pathways.High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patientsTherapeutic resistance in lung cancer.Clinical relevance of the homologous recombination machinery in cancer therapy.DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.Targeting homologous recombination-mediated DNA repair in cancer.A phase I, first-in-human dose-escalation study of amuvatinib, a multi-targeted tyrosine kinase inhibitor, in patients with advanced solid tumors.Chemotherapy Resistance in Lung Cancer.Delineation of key XRCC4/Ligase IV interfaces for targeted disruption of non-homologous end joining DNA repair.RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma.Safety, tolerability, and pharmacokinetics of amuvatinib from three phase 1 clinical studies in healthy volunteers.Exploiting the homologous recombination DNA repair network for targeted cancer therapy.Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics.A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin.Plasma and cerebrospinal fluid pharmacokinetics of MP470 in non-human primates.Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.A phase 2, open-label, multi-center study of amuvatinib in combination with platinum etoposide chemotherapy in platinum-refractory small cell lung cancer patients.Impact of RAD51C-mediated Homologous Recombination on Genomic Integrity in Barrett's Adenocarcinoma Cells.Inhibition of RAD51 by siRNA and Resveratrol Sensitizes Cancer Stem Cells Derived from HeLa Cell Cultures to Apoptosis.The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer.Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeomeRPA and RAD51: fork reversal, fork protection, and genome stability
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P1343
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P2860
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
@en
The role of RAD51 in etoposide
@nl
type
label
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
@en
The role of RAD51 in etoposide
@nl
prefLabel
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
@en
The role of RAD51 in etoposide
@nl
P2093
P4510
P356
P1476
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
@en
P2093
Cecilia Lundin
Lasse Tengbjerg Hansen
Lone Nørgård Petersen
Mogens Spang-Thomsen
P304
P356
10.1002/IJC.11106
P577
2003-07-01T00:00:00Z