Targeting homologous recombination-mediated DNA repair in cancer. - Test2 - elhamkhani - TriplyDB

Targeting homologous recombination-mediated DNA repair in cancer.

Targeting homologous recombination-mediated DNA repair in cancer.

http://www.wikidata.org/entity/Q38184667

about

Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMO Predictive biomarkers for triple negative breast cancer treated with platinum-based chemotherapy.Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.Genetic Manipulation of Homologous Recombination In Vivo Attenuates Intestinal Tumorigenesis.Caffeine inhibits gene conversion by displacing Rad51 from ssDNA.Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma.Synergistic potentiation of (-)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821.Radiobiological modifiers in clinical radiation oncology: current reality and future potential.Regulation of recombination and genomic maintenance.INPP4B-mediated DNA repair pathway confers resistance to chemotherapy in acute myeloid leukemia.Resisting resistance: is there a solution for malaria?A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment.Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors.Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells.H-Ferritin-nanocaged olaparib: a promising choice for both BRCA-mutated and sporadic triple negative breast cancer A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin.Ginsenosides synergize with mitomycin C in combating human non-small cell lung cancer by repressing Rad51-mediated DNA repair.High expression of Rad51c predicts poor prognostic outcome and induces cell resistance to cisplatin and radiation in non-small cell lung cancer.Comment on: targeting homologous recombination-mediated DNA repair in cancer

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Targeting homologous recombination-mediated DNA repair in cancer.

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Targeting homologous recombination-mediated DNA repair in cancer.

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Targeting homologous recombination-mediated DNA repair in cancer.

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14728222.2014.882900

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Expert Opinion on Therapeutic Targets

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Targeting homologous recombination-mediated DNA repair in cancer.

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João F S Carvalho

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Roland Kanaar

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P2860

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis

Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

The RecQ DNA helicases in DNA repair

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427-458

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scholarly article

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10.1517/14728222.2014.882900

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4

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