Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
about
Using the deadly mu-conotoxins as probes of voltage-gated sodium channelsFolding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4.Molecular dynamics study of binding of µ-conotoxin GIIIA to the voltage-gated sodium channel Na(v)1.4.Novel interactions identified between micro -Conotoxin and the Na+ channel domain I P-loop: implications for toxin-pore binding geometry.Biophysical properties of Na(v) 1.8/Na(v) 1.2 chimeras and inhibition by µO-conotoxin MrVIB.Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.The tetrodotoxin receptor of voltage-gated sodium channels--perspectives from interactions with micro-conotoxins.Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands.
P2860
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P2860
Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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name
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@en
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@nl
type
label
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@en
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@nl
prefLabel
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@en
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@nl
P2093
P2860
P356
P1476
Dependence of mu-conotoxin blo ...... s and their molecular targets.
@en
P2093
Charles A Henrikson
Eduardo Marbán
Gordon F Tomaselli
Kazuki Sato
Kwokyin Hui
Robert J French
Ronald A Li
P2860
P304
30912-30919
P356
10.1074/JBC.M301039200
P407
P577
2003-05-21T00:00:00Z