The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
about
Deubiquitylating enzymes and diseaseE3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1)Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53CARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradationThe infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activityTRIM family proteins: retroviral restriction and antiviral defenceMacrophages and cytokines in the early defence against herpes simplex virusOcular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?The potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1HSV-1 ICP0: paving the way for viral replicationThe topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressorA RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defenceNuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infectionVy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.The major tegument structural protein VP22 targets areas of dispersed nucleolin and marginalized chromatin during productive herpes simplex virus 1 infection.Characterization of the subcellular localization of herpes simplex virus type 1 proteins in living cells.HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate ImmunityNovel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication.Expression and mutational analysis of Autographa californica nucleopolyhedrovirus HCF-1: functional requirements for cysteine residues.A deubiquitinating activity is conserved in the large tegument protein of the herpesviridaeCentromere architecture breakdown induced by the viral E3 ubiquitin ligase ICP0 protein of herpes simplex virus type 1.Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity.Making sense of ubiquitin ligases that regulate p53.ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.Trim-cyclophilin A fusion proteins can restrict human immunodeficiency virus type 1 infection at two distinct phases in the viral life cycle.White spot syndrome virus open reading frame 222 encodes a viral E3 ligase and mediates degradation of a host tumor suppressor via ubiquitination.A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation.Herpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation.Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation.Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system.Cytoplasmic localized infected cell protein 0 (bICP0) encoded by bovine herpesvirus 1 inhibits β interferon promoter activity and reduces IRF3 (interferon response factor 3) protein levels.Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus ReplicationA quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitroOverexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expressionN-terminal phosphorylation sites of herpes simplex virus 1 ICP0 differentially regulate its activities and enhance viral replication.The zinc RING finger of bovine herpesvirus 1-encoded bICP0 protein is crucial for viral replication and virulence.Ocular HSV-1 latency, reactivation and recurrent disease.
P2860
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P2860
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
The herpes simplex virus type ...... ts with and Ubiquitinates p53.
@en
type
label
The herpes simplex virus type ...... ts with and Ubiquitinates p53.
@en
prefLabel
The herpes simplex virus type ...... ts with and Ubiquitinates p53.
@en
P2860
P356
P1476
The herpes simplex virus type ...... ts with and Ubiquitinates p53.
@en
P2093
Roger D Everett
P2860
P304
36596-36602
P356
10.1074/JBC.M300776200
P407
P577
2003-07-09T00:00:00Z