Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
about
Mechanistic and functional versatility of radical SAM enzymesRlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNAReconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamilySPASM and twitch domains in S-adenosylmethionine (SAM) radical enzymesX-ray structure of the [FeFe]-hydrogenase maturase HydE from Thermotoga maritimaStructures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactionsMitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients.The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasitesCharacterization of an active spore photoproduct lyase, a DNA repair enzyme in the radical S-adenosylmethionine superfamilyCharacterization of quinolinate synthases from Escherichia coli, Mycobacterium tuberculosis, and Pyrococcus horikoshii indicates that [4Fe-4S] clusters are common cofactors throughout this class of enzymesFunctional studies of [FeFe] hydrogenase maturation in an Escherichia coli biosynthetic system.Radical SAM enzymes in methylation and methylthiolationGlycyl radical activating enzymes: structure, mechanism, and substrate interactionsEmerging themes in radical SAM chemistryQuinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis.Biotin and Lipoic Acid: Synthesis, Attachment, and Regulation.The biosynthesis of thiol- and thioether-containing cofactors and secondary metabolites catalyzed by radical S-adenosylmethionine enzymes.NsrR from Streptomyces coelicolor is a nitric oxide-sensing [4Fe-4S] cluster protein with a specialized regulatory function.Identification and characterization of functional homologs of nitrogenase cofactor biosynthesis protein NifB from methanogens.Analysis of ThiC variants in the context of the metabolic network of Salmonella enterica.Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.RimO, a MiaB-like enzyme, methylthiolates the universally conserved Asp88 residue of ribosomal protein S12 in Escherichia coli.Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.Self-sacrifice in radical S-adenosylmethionine proteins.Crystallographic snapshots of sulfur insertion by lipoyl synthase.The thiamine biosynthetic enzyme ThiC catalyzes multiple turnovers and is inhibited by S-adenosylmethionine (AdoMet) metabolitesCharacterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.Radical S-adenosylmethionine enzymes.Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors.Identification of an intermediate methyl carrier in the radical S-adenosylmethionine methylthiotransferases RimO and MiaB.Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis.Evidence for a catalytically and kinetically competent enzyme-substrate cross-linked intermediate in catalysis by lipoyl synthaseFurther characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.Reduction of the [2Fe-2S] cluster accompanies formation of the intermediate 9-mercaptodethiobiotin in Escherichia coli biotin synthase.9-Mercaptodethiobiotin is formed as a competent catalytic intermediate by Escherichia coli biotin synthase.Transformations of the FeS Clusters of the Methylthiotransferases MiaB and RimO, Detected by Direct Electrochemistry.Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamilyBiochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima.
P2860
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P2860
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@en
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@nl
type
label
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@en
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@nl
prefLabel
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@en
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@nl
P2093
P356
P1433
P1476
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide.
@en
P2093
Camelia Baleanu-Gogonea
Kyung-Hoon Lee
Natasha M Nesbitt
Robert M Cicchillo
Squire J Booker
P304
11770-11781
P356
10.1021/BI0488505
P407
P577
2004-09-01T00:00:00Z