Negative regulation of TCF-dependent signaling by WNT ligand antagonists - Test2 - elhamkhani - TriplyDB

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

http://www.wikidata.org/entity/Q45318257

about

DKK and KRM bind LRP5/6 DKK promotes clathrin-dependent internalization of LRP6 SOST binds LRP5/6 WIF1 binds WNTs sFRP binds WNT3A and inhibits WNT:FZD binding

P361

TCF dependent signaling in response to WNT

P527

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P361

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P527

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

http://www.wikidata.org/entity/Q45318257

description

An instance of the biological ...... nd antagonists in Homo sapiens

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name

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

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type

label

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

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prefLabel

Negative regulation of TCF-dependent signaling by WNT ligand antagonists

@en

P2860

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P2888

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P361

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P3937

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P703

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P2860

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins

Secreted antagonists of the Wnt signalling pathway

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

Function and biological roles of the Dickkopf family of Wnt modulators.

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.

P2888

reactome:R-HSA-3772470

P31

negative regulation of canonical Wnt signaling pathway

biological pathway

P361

TCF dependent signaling in response to WNT

P3937

R-HSA-3772470

http://www.w3.org/2001/XMLSchema#string

P527

DKK and KRM bind LRP5/6

DKK promotes clathrin-dependent internalization of LRP6

SOST binds LRP5/6

WIF1 binds WNTs

sFRP binds WNT3A and inhibits WNT:FZD binding

P703