about
ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosisAnkyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradationFunctional analysis of Asb-1 using genetic modification in miceERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specificationThrombocytopenia and kidney disease in mice with a mutation in the C1galt1 geneConserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian MammalsCHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairmentThe dendritic cell receptor Clec9A binds damaged cells via exposed actin filamentsFunctional genetic analysis of mouse chromosome 11The SOCS box: a tale of destruction and degradationThe transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cellsMutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopeniaA mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasisAgm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and developmentPoint mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- miceA new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelinationTwo ENU-induced alleles of Atp2b2 cause deafness in mice.Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.Programmed anuclear cell death delimits platelet life span.Mutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopeniaDual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia.Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets.Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function.Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human plateletsA model for studying the hemostatic consumption or destruction of plateletsLoss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.The role of apoptosis in megakaryocytes and platelets.Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia.BCL-2 is dispensable for thrombopoiesis and platelet survivalMice Haploinsufficient for Ets1 and Fli1 Display Middle Ear Abnormalities and Model Aspects of Jacobsen Syndrome.Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1).Regulation of platelet lifespan in the presence and absence of thrombopoietin signaling.Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.
P50
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description
Australian molecular geneticist
@en
geneticus
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name
Benjamin T. Kile
@ast
Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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type
label
Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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altLabel
Benjamin Kile
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Benjamin T Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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Benjamin T. Kile
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P1053
F-6593-2011
P106
P1153
57205974953
P21
P31
P3829
P4012
P496
0000-0002-8836-8947