ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification - Test2 - elhamkhani - TriplyDB

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

http://www.wikidata.org/entity/Q24629886

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Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis The role of GATA2 in lethal prostate cancer aggressiveness.Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease.TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation Erg cooperates with TGF-β to control mesenchymal differentiation.Decoding the regulatory network of early blood development from single-cell gene expression measurements.Early lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model.Oncogenic activation of ERG: A predominant mechanism in prostate cancer.Aberrant expression of miR-9/9* in myeloid progenitors inhibits neutrophil differentiation by post-transcriptional regulation of ERG.Hematopoietic stem cells: transcriptional regulation, ex vivo expansion and clinical application.Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells.Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia.ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorder Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cells A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.B-lineage transcription factors and cooperating gene lesions required for leukemia development.ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells ETS-dependent regulation of a distal Gata4 cardiac enhancer.Emergence of ETS transcription factors as diagnostic tools and therapeutic targets in prostate cancer.The ERGonomics of hematopoietic stem cell self-renewal.BAALC and ERG Expression in Egyptian Patients with Acute Myeloid Leukemia, Relation to Survival and Response to Treatment.ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.Direct reprogramming of murine fibroblasts to hematopoietic progenitor cells.The transcriptional landscape of hematopoietic stem cell ontogeny An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells.Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis.Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells.

P2860

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P2860

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

http://www.wikidata.org/entity/Q24629886

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

ERG dependence distinguishes d ...... om hematopoietic specification

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ERG dependence distinguishes d ...... om hematopoietic specification

@en

ERG dependence distinguishes d ...... om hematopoietic specification

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type

label

ERG dependence distinguishes d ...... om hematopoietic specification

@ast

ERG dependence distinguishes d ...... om hematopoietic specification

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ERG dependence distinguishes d ...... om hematopoietic specification

@nl

prefLabel

ERG dependence distinguishes d ...... om hematopoietic specification

@ast

ERG dependence distinguishes d ...... om hematopoietic specification

@en

ERG dependence distinguishes d ...... om hematopoietic specification

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Genes & Development

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ERG dependence distinguishes d ...... om hematopoietic specification

@en

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Adrienne Hilton

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Anne K Voss

http://www.w3.org/2001/XMLSchema#string

Caitlin Collin

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John E Pimanda

http://www.w3.org/2001/XMLSchema#string

Julie Scott

http://www.w3.org/2001/XMLSchema#string

Kathy Knezevic

http://www.w3.org/2001/XMLSchema#string

Thomas Bee

http://www.w3.org/2001/XMLSchema#string

Tim Thomas

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Tracy A Willson

http://www.w3.org/2001/XMLSchema#string

Warren S Alexander

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P2860

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

Circulation and chemotaxis of fetal hematopoietic stem cells

Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

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251-62

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scholarly article

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1444232

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10.1101/GAD.2009211

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3

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25

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Benjamin T. Kile

Douglas J. Hilton

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2011-02-01T00:00:00Z

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49765143

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21245161

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3034900

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