Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.
about
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptorCreating an 7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein: CRYSTALLOGRAPHIC AND LIGAND SELECTIVITY ANALYSESMultiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptorsNicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptorTreating schizophrenia symptoms with an alpha7 nicotinic agonist, from mice to men.High throughput electrophysiology with Xenopus oocytesThe binding orientations of structurally-related ligands can differ; A cautionary noteCharacterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors.5-HT3 receptor-dependent modulation of respiratory burst frequency, regularity, and episodicity in isolated adult turtle brainstemsMerging old and new perspectives on nicotinic acetylcholine receptorsTropisetron increases the inhibitory effect of mild restraint on lordosis behavior of hormonally primed, ovariectomized rats.Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states.The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusionFrom Chemotherapy-Induced Emesis to Neuroprotection: Therapeutic Opportunities for 5-HT3 Receptor Antagonists.Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.Synthesis and Cytotoxicity Evaluation of Tropinone Derivatives.Tropisetron as a neuroprotective agent against glutamate-induced excitotoxicity and mechanisms of action.The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials.Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391.Sympathetic α₃β₂-nAChRs mediate cerebral neurogenic nitrergic vasodilation in the swine.A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand.
P2860
Q27657109-B5B86E1F-7BDF-4278-9904-E7E0F0A8F3EAQ27675116-9092849B-3124-480C-90C8-4CB6E840EEB3Q30371843-9D5731A4-EDBB-4035-B8E1-9823B96E2AABQ30453198-A407D5B5-A420-4AEC-AD20-36E4E0CD7827Q30493072-B828D7D3-F0CE-4399-90AF-6204FEF3FE2FQ33400496-1BA97685-6B36-4A93-B9FF-4E33AB0425E3Q33777929-85DE7D5C-3E25-4277-8799-31C14303C8EFQ33815991-0E39A97A-D087-4544-AE9D-2A88F44ADFFEQ33999221-19B3ADA5-422C-4489-91F3-F1AA22F1023BQ34401492-6504D3C9-2C38-4496-8B8C-62C96A8BCD9EQ34709203-F25A1F1C-D964-44AF-9279-BC444A570271Q35586093-D4C678D2-74A9-422F-A051-5689F15439E9Q36670497-0F0D9BA9-880F-4998-9656-1709E584CB40Q38265931-39148542-8A99-4FA5-AB52-83D7B5022846Q39461570-3B32BADD-BF75-4C09-B0D8-36D165CB4F0FQ42058614-A72E0B0A-A412-4A42-8173-9C38F44B2EA0Q42120726-394AE024-D6A6-480A-9D02-9561D246DD45Q47127039-C49FE194-09B2-4B60-A46E-178DE57F35F6Q48343689-91DE4723-944E-4EED-967F-08727F768BB7Q48674733-2BA2B5E9-F9B6-41A1-8ECB-F53FA35AF3D5Q52147865-17D7A419-D225-48F4-AE7E-A13583D6248C
P2860
Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Molecular dissection of tropis ...... tor-selective partial agonist.
@en
Molecular dissection of tropis ...... tor-selective partial agonist.
@nl
type
label
Molecular dissection of tropis ...... tor-selective partial agonist.
@en
Molecular dissection of tropis ...... tor-selective partial agonist.
@nl
prefLabel
Molecular dissection of tropis ...... tor-selective partial agonist.
@en
Molecular dissection of tropis ...... tor-selective partial agonist.
@nl
P2093
P1433
P1476
Molecular dissection of tropis ...... tor-selective partial agonist.
@en
P2093
Brian A Jack
Hillary C Schiff
Nicole A Horenstein
Roger L Papke
P304
P356
10.1016/J.NEULET.2004.12.025
P407
P577
2005-01-05T00:00:00Z