Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model.
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Insulin-like growth factors promote vasculogenesis in embryonic stem cellsIdentification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptorModulation of insulin-like growth factor-1 receptor and its signaling network for the treatment of cancer: current status and future perspectivesThe insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potentialA heterogeneous in vitro three dimensional model of tumour-stroma interactions regulating sprouting angiogenesisMolecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanismInhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines.Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationInsulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma.The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation.Inhibition of type I insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma.Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukaemia cellsMultiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications.Maintenance therapy in multiple myeloma.Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.Insulin-like growth factor: current concepts and new developments in cancer therapy.IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.The role of the insulin-like growth factor 1 receptor axis in multiple myeloma.Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myelomaMouse models as a translational platform for the development of new therapeutic agents in multiple myeloma.IGF-IR and its inhibitors in gastrointestinal carcinomas (Review).Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.Microenvironment drug resistance in multiple myeloma: emerging new players.Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.Antitumour and antiangiogenic effects of Aplidin in the 5TMM syngeneic models of multiple myelomaDifferential localization of MT1-MMP in human prostate cancer tissue: role of IGF-1R in MT1-MMP expression.Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: a new potential therapy for the treatment of melanoma.Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivoTotal synthesis of (±)-epithuriferic acid methyl ester via Diels-Alder reaction.
P2860
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P2860
Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@en
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@nl
type
label
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@en
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@nl
prefLabel
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@en
Inhibiting the IGF-1 receptor ...... udy in the 5T33MM mouse model.
@nl
P2093
P1433
P1476
Inhibiting the IGF-1 receptor ...... tudy in the 5T33MM mouse model
@en
P2093
Ben Van Camp
Helena Jernberg-Wiklund
Hendrik De Raeve
Karin Vanderkerken
Kenneth Nilsson
Kewal Asosingh
Magnus Axelson
Olle Larsson
Thomas Stromberg
P304
P356
10.1182/BLOOD-2005-01-0293
P407
P577
2005-07-26T00:00:00Z