WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.

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WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

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WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

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WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

@en

WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

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WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

@en

WWC2 is an independent prognos ...... g in hepatocellular carcinoma.

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P1476

WWC2 is an independent prognos ...... ng in hepatocellular carcinoma

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Caixia Gan

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Dong Chen

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Jiahuai Wen

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Jiangbo Zhang

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Jiewei Chen

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Joachim Kremerskothen

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Shilu Chen

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Shumei Yan

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Yan Li

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Yun Cao

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Evolutionary and molecular facts link the WWC protein family to Hippo signaling

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

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3718-3729

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scholarly article

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10.1111/JCMM.13281

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P478

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Yijun Zhang

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2017-08-16T00:00:00Z

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28815883

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5706493

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