Genetic associations with human longevity at the APOE and ACE loci.
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We are ageingEstablishment of induced pluripotent stem cells from centenarians for neurodegenerative disease researchDNA methylation age of blood predicts all-cause mortality in later lifeEvidence that the gene encoding insulin degrading enzyme influences human lifespanGenome-environment interactions that modulate aging: powerful targets for drug discoveryAmino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphismPolymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of dataCardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC.APOE genotype and stress response - a mini reviewHuman longevity: Genetics or Lifestyle? It takes two to tangoEndothelin-converting enzymes and related metalloproteases in Alzheimer's diseaseThe search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individualsComputationally Modeling Lipid Metabolism and Aging: A Mini-reviewThe glutamatergic system and neurodegeneration in dementia: preventive strategies in Alzheimer's diseaseReduced hippocampal volume in healthy young ApoE4 carriers: an MRI studyGenetic signatures of exceptional longevity in humansCauses, effects, and constraints in the genetics of human longevity.Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures.Distinct patterns of brain activity in young carriers of the APOE-epsilon4 alleleThe Neurobiology and Age-Related Prevalence of the ε4 Allele of Apolipoprotein E in Alzheimer's Disease Cohorts.The genetics of aging-- implications for pharmacogenomics.Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene.Life-long sustained mortality advantage of siblings of centenarians.Genetic and environmental influences on exceptional longevity and the AGE nomogram.RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.Selection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E.Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population.Discovery of a brain promoter from the human transferrin gene and its utilization for development of transgenic mice that express human apolipoprotein E alleles.The evolutionary genetics of ageing and longevity.The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years.High-density genomewide linkage analysis of exceptional human longevity identifies multiple novel loci.Adjustment for smoking does not alter the FOXO3A association with longevity.Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan.What geriatricians should know about the Werner syndrome.Incidence of amyotrophic lateral sclerosis in Europe.APOE gene polymorphism in long-lived individuals from a central China population.Are 'endurance' alleles 'survival' alleles? Insights from the ACTN3 R577X polymorphism.Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
P2860
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P2860
Genetic associations with human longevity at the APOE and ACE loci.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Genetic associations with human longevity at the APOE and ACE loci.
@en
Genetic associations with human longevity at the APOE and ACE loci.
@nl
type
label
Genetic associations with human longevity at the APOE and ACE loci.
@en
Genetic associations with human longevity at the APOE and ACE loci.
@nl
altLabel
Genetic associations with human longevity at the APOE and ACE loci
@en
prefLabel
Genetic associations with human longevity at the APOE and ACE loci.
@en
Genetic associations with human longevity at the APOE and ACE loci.
@nl
P2093
P356
P1433
P1476
Genetic associations with human longevity at the APOE and ACE loci.
@en
P2093
Faure-Delanef L
Lesueur-Ginot L
Schächter F
P2888
P356
10.1038/NG0194-29
P407
P577
1994-01-01T00:00:00Z