Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease.
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Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activitiesMolecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision MedicineAdult Astrogenesis and the Etiology of Cortical NeurodegenerationFriends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative DiseasesGlia and alpha-synuclein in neurodegeneration: A complex interactionThe complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseAlpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivoSystems biology of neurodegenerative diseasesRole of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative DiseasesParkinson's disease as a result of agingAntidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophyMechanisms underlying inflammation in neurodegenerationAstrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease.Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.CSF from Parkinson disease patients differentially affects cultured microglia and astrocytes.Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.Functional connectivity fMRI of the rodent brain: comparison of functional connectivity networks in rat and mouseBrain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson's disease.Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?The many faces of α-synuclein: from structure and toxicity to therapeutic target.Astrocytic dynamin-like protein 1 regulates neuronal protection against excitotoxicity in Parkinson disease.Expression of mutant alpha-synuclein modulates microglial phenotype in vitroConditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction.Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein.Heat shock protein defenses in the neocortex and allocortex of the telencephalon.Electroacupuncture remediates glial dysfunction and ameliorates neurodegeneration in the astrocytic α-synuclein mutant mouse modelLesion profiling and subcellular prion localization of cervid chronic wasting disease in domestic cats.Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes.The Interplay between Alpha-Synuclein Clearance and SpreadingDementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis.Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway.Combination therapies: The next logical Step for the treatment of synucleinopathies?Can we clinically diagnose dementia with Lewy bodies yet?Multiple system atrophy: a primary oligodendrogliopathy.Pathologic modifications of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated squirrel monkeysInflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
P2860
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P2860
Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@en
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@nl
type
label
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@en
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@nl
prefLabel
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@en
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@nl
P2093
P921
P1476
Development of alpha-synuclein ...... sporadic Parkinson's disease.
@en
P2093
Heiko Braak
Kelly Del Tredici
Magdalena Sastre
P2888
P304
P356
10.1007/S00401-007-0244-3
P577
2007-06-19T00:00:00Z