Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis.
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Antibiotics from predatory bacteriaDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Lessons learned from the transformation of natural product discovery to a genome-driven endeavorEvolutionary implications of bacterial polyketide synthasesNovel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.Adaptation of an L-proline adenylation domain to use 4-propyl-L-proline in the evolution of lincosamide biosynthesisAurafuron A and B, new bioactive polyketides from Stigmatella aurantiaca and Archangium gephyra (Myxobacteria). Fermentation, isolation, physico-chemical properties, structure and biological activity.Two classes of new peptaibols are synthesized by a single non-ribosomal peptide synthetase of Trichoderma virens.The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulationThe 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products.A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis.Fungal cyclooligomer depsipeptides: from classical biochemistry to combinatorial biosynthesis.Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics.Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis.Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase.Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthusNovel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2.In vivo characterization of nonribosomal peptide synthetases NocA and NocB in the biosynthesis of nocardicin A.Identification and characterization of the cuevaene A biosynthetic gene cluster in streptomyces sp. LZ35.Genome-based cryptic gene discovery and functional identification of NRPS siderophore peptide in Streptomyces peucetius.Discovery of a new peptide natural product by Streptomyces coelicolor genome mining.Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining.Discovery of the rhizopodin biosynthetic gene cluster in Stigmatella aurantiaca Sg a15 by genome mining.A unique mechanism for methyl ester formation via an amide intermediate found in myxobacteria.Module and individual domain deletions of NRPS to produce plipastatin derivatives in Bacillus subtilis.Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production
P2860
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P2860
Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@en
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@nl
type
label
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@en
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@nl
prefLabel
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@en
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@nl
P2093
P2860
P356
P1433
P1476
Structure and biosynthesis of ...... ibosomal peptide biosynthesis.
@en
P2093
Barbara Silakowski
Brigitte Kunze
Gerhard Höfle
Helmut Blöcker
Maren Scharfe
Silke C Wenzel
P2860
P304
P356
10.1002/CBIC.200400282
P50
P577
2005-02-01T00:00:00Z