Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways. - Test2 - elhamkhani - TriplyDB

Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways.

Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways.

http://www.wikidata.org/entity/Q48238418

about

Software applications for flux balance analysis Recent Developments in Systems Biology and Metabolic Engineering of Plant-Microbe Interactions.Computational Methods for Modification of Metabolic Networks Analysis of genetic variation and potential applications in genome-scale metabolic modeling In Silico Constraint-Based Strain Optimization Methods: the Quest for Optimal Cell Factories AlgaGEM--a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome OptFlux: an open-source software platform for in silico metabolic engineering Computational design of auxotrophy-dependent microbial biosensors for combinatorial metabolic engineering experiments Identification of functional differences in metabolic networks using comparative genomics and constraint-based models ReacKnock: identifying reaction deletion strategies for microbial strain optimization based on genome-scale metabolic network Enumeration of smallest intervention strategies in genome-scale metabolic networks k-OptForce: integrating kinetics with flux balance analysis for strain design Metabolic engineering of a novel muconic acid biosynthesis pathway via 4-hydroxybenzoic acid in Escherichia coli Cyanobacterial biofuels: new insights and strain design strategies revealed by computational modeling Identification of metabolic engineering targets through analysis of optimal and sub-optimal routes IMGMD: A platform for the integration and standardisation of In silico Microbial Genome-scale Metabolic Models Synthetic and systems biology for microbial production of commodity chemicals.Engineering glucose metabolism of Escherichia coli under nitrogen starvation.Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease.Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods Prediction of microbial growth rate versus biomass yield by a metabolic network with kinetic parameters The virus as metabolic engineer.Chapter 12: Human microbiome analysis Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load Computing smallest intervention strategies for multiple metabolic networks in a boolean model.Design of optimally constructed metabolic networks of minimal functionality.RobOKoD: microbial strain design for (over)production of target compounds.Flux-sum analysis identifies metabolite targets for strain improvement A systems biology approach to reconcile metabolic network models with application to Synechocystis sp. PCC 6803 for biofuel production.Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement Applications of genome-scale metabolic network model in metabolic engineering.Genome-scale modeling for metabolic engineering.FastPros: screening of reaction knockout strategies for metabolic engineering.Seeing the wood for the trees: a forest of methods for optimization and omic-network integration in metabolic modelling.Application of theoretical methods to increase succinate production in engineered strains.Constraint-based stoichiometric modelling from single organisms to microbial communities.In silico design of anaerobic growth-coupled product formation in Escherichia coli: experimental validation using a simple polyol, glycerol.Engineering biological systems using automated biofoundries.

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Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways.

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Predicting metabolic engineeri ...... unting for competing pathways.

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Tomer Shlomi

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P2860

An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

Genome-scale models of microbial cells: evaluating the consequences of constraints

Fat synthesis in adipose tissue. An examination of stoichiometric constraints

Metabolic network analysis integrated with transcript verification for sequenced genomes.

The commercial production of chemicals using pathway engineering.

Advances in flux balance analysis.

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536-543

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10.1093/BIOINFORMATICS/BTP704

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26

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20031969

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