HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

@en

HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

@nl

P1476

HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes

@en

P2093

Carlo Baggio

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Claudio Luchinat

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Maurizio Pellecchia

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P2860

Recent developments in fragment-based drug discovery

‘Unconventional’ Coordination Chemistry by Metal Chelating Fragments in a Metalloprotein Active Site

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Discovering high-affinity ligands for proteins: SAR by NMR

Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.

Synthesis and screening of positional scanning combinatorial libraries.

Informatics and modeling challenges in fragment-based drug discovery.

ABT-199, a new Bcl-2-specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia.

Chelator fragment libraries for targeting metalloproteinases.

P304

137-142

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.7B00483

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P433

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P478

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P50

Marco Fragai

Linda Cerofolini

P577

2018-01-17T00:00:00Z

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P698

29456802

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P932

5807865

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