An enantioselective enzymatic desymmetrization route to hexahydro-4H-furopyranol, a high-affinity ligand for HIV-1 protease inhibitors.

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An enantioselective enzymatic desymmetrization route to hexahydro-4H-furopyranol, a high-affinity ligand for HIV-1 protease inhibitors.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

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An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

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Item

label

An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

@en

An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

@nl

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An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

@en

An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

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P1476

An enantioselective enzymatic ...... for HIV-1 protease inhibitors.

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P2093

Anindya Sarkar

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Arun K Ghosh

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P2860

Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV

Ending the HIV-AIDS Pandemic--Follow the Science.

Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study.

Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.

Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.

Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114

Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro.

Bis-tetrahydrofuran: a privileged ligand for darunavir and a new generation of hiv protease inhibitors that combat drug resistance.

Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance.

Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor.

P304

3230-3233

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scholarly article

P356

10.1016/J.TETLET.2017.07.010

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P433

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P478

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P577

2017-07-03T00:00:00Z

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P698

29200514

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P921

enantioselectivity

P932

5708567

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