about
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formationHuman AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)A role for Xrcc2 in the early stages of mouse developmentHaem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.The Succinated Proteome of FH-Mutant TumoursRenal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore ExpansionExpression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.Rare insights into cancer biology.Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.Cells lacking the fumarase tumor suppressor are protected from apoptosis through a hypoxia-inducible factor-independent, AMPK-dependent mechanism.Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.The emerging role of fumarate as an oncometabolite.Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive DiabetesNovel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signallingExpression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.Purine nucleotide metabolism regulates expression of the human immune ligand MICA.Xrcc2 modulates spontaneous and radiation-induced tumorigenesis in Apcmin/+ mice.A simple and efficient procedure for non-isotopic in situ hybridization to sectioned material.Patterns of haemopoietic recovery after stress--II. Treatment with fluorouracil.The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPasesPHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodiesPublisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPasesMaintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retinaInsulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretionInterleukin-1 Beta Gene Deregulation Associated With Chromosomal Rearrangement: A Candidate Initiating Event for Murine Radiation-Myeloid Leukemogenesis?Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP ProductionDNA methylation changes in the IL-1 (2F) chromosomal region of some radiation-induced acute myeloid leukaemias carrying chromosome 2 rearrangementsThe IL-1 alpha and beta genes are closely linked (less than 70 kb) on mouse chromosome 2Patterns of recovery of high proliferation potential colony-forming cells after stressing the haemopoietic system--IAssessing cultured colonies automaticallyComparative bioenergetic assessment of transformed cells using a cell energy budget platformIn the ring with polycystic kidney disease--avoiding the knockout punch
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P50
description
Canadees onderzoekster
@nl
hulumtuese
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kanadische Forscherin
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researcher
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ricercatrice
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հետազոտող
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name
Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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type
label
Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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prefLabel
Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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Julie Adam
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0000-0002-7980-7151
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2147201410
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lccn-n90695633