Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency. - Test2 - elhamkhani - TriplyDB

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

http://www.wikidata.org/entity/Q36742515

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Mitochondrial metabolic remodeling in response to genetic and environmental perturbations Defects in mitochondrial metabolism and cancer Oncometabolites: Unconventional triggers of oncogenic signalling cascades Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease The succinated proteome.Uterine smooth muscle tumors with features suggesting fumarate hydratase aberration: detailed morphologic analysis and correlation with S-(2-succino)-cysteine immunohistochemistry.Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.Mitochondrial Deficiencies in the Predisposition to Paraganglioma The Succinated Proteome of FH-Mutant Tumours Oncometabolites: linking altered metabolism with cancer.Identification of protein succination as a novel modification of tubulin Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.Complex role of HIF in cancer: the known, the unknown, and the unexpected.Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions.Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry.Rare insights into cancer biology.Metabolic control of signalling pathways and metabolic auto-regulation.Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.Leiomyoma with bizarre nuclei: a morphological, immunohistochemical and molecular analysis of 31 cases.SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.Molecular Pathogenesis and Diagnostic, Prognostic and Predictive Molecular Markers in Sarcoma.Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors.Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas.Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes Exploiting tumor metabolism: challenges for clinical translation.Adipocyte protein modification by Krebs cycle intermediates and fumarate ester-derived succination.Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes.Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects.The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.Metabolic Alterations in Cancer Cells and the Emerging Role of Oncometabolites as Drivers of Neoplastic Change.Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma.Identification of a metabolic disposal route for the oncometabolite S-(2-succino)cysteine in Bacillus subtilis.Mitochondrial Complex I activity signals antioxidant response through ERK5.Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation

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Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

http://www.wikidata.org/entity/Q36742515

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

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2013年论文

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2013年论文

@zh-cn

name

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@ast

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@en

type

label

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@ast

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@en

prefLabel

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@ast

Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

@en

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J.CELREP.2013.02.013

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Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency.

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Alexandre Berquand

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Kaori Igarashi

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Kaori Saito

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Kathryn Wolhulter

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Keiko Kato

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Linda O'Flaherty

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Mahima Laroyia

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Ming Yang

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Mitsuhiro Kitagawa

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Norma Frizzell

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689-700

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10.1016/J.CELREP.2013.02.013

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3

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3

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Benedikt M. Kessler

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Nicola Ternette

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2013-03-14T00:00:00Z

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236053843

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23499446

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