Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.
about
Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFs.The yin and yang of yeast: biodiversity research and systems biology as complementary forces driving innovation in biotechnology.Model based engineering of Pichia pastoris central metabolism enhances recombinant protein productionGenome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvementGenome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentialsGenome-scale metabolic model of the fission yeast Schizosaccharomyces pombe and the reconciliation of in silico/in vivo mutant growthGenome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1.Systems-level organization of yeast methylotrophic lifestyle.Integration and Validation of the Genome-Scale Metabolic Models of Pichia pastoris: A Comprehensive Update of Protein Glycosylation Pathways, Lipid and Energy MetabolismDynamic genome-scale metabolic modeling of the yeast Pichia pastorisPichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates.Can microbes compete with cows for sustainable protein production - A feasibility study on high quality protein.Metabolic reconstruction and flux analysis of industrial Pichia yeasts.Pichia pastoris: protein production host and model organism for biomedical research.New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris.Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels.Microbials for the production of monoclonal antibodies and antibody fragments.Improving the secretory production of the heterologous protein in Pichia pastoris by focusing on protein folding.Applications of genome-scale metabolic network model in metabolic engineering.Improving functional annotation for industrial microbes: a case study with Pichia pastoris.Optimizing eukaryotic cell hosts for protein production through systems biotechnology and genome-scale modeling.Metabolic modeling to identify engineering targets for Komagataella phaffii: The effect of biomass composition on gene target identification.Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris.Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures.Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization.Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary ¹³C flux analysis.Development of quantitative metabolomics for Pichia pastoris.Biomarkers to evaluate the effects of temperature and methanol on recombinant Pichia pastoris.Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions.Genome-scale modeling of yeast: chronology, applications and critical perspectives.Fine-tuning the P. pastoris iMT1026 genome-scale metabolic model for improved prediction of growth on methanol or glycerol as sole carbon sources.Integrating metabolic modeling and population heterogeneity analysis into optimizing recombinant protein production by Komagataella (Pichia) pastoris.Systems biotechnology for protein production in Pichia pastoris.Functional analysis of alcohol dehydrogenase (ADH) genes in Pichia pastoris.Hygromycin-resistance vectors for gene expression in Pichia pastoris.A macrokinetic model-based comparative meta-analysis of recombinant protein production by Pichia pastoris under AOX1 promoter.Hybrid metabolic flux analysis and recombinant protein prediction in Pichia pastoris X-33 cultures expressing a single-chain antibody fragment.Genome-based kinetic modeling of cytosolic glucose metabolism in industrially relevant cell lines: Saccharomyces cerevisiae and Chinese hamster ovary cells.Genome-scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins.iOD907, the first genome-scale metabolic model for the milk yeast Kluyveromyces lactis.
P2860
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P2860
Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Genome-scale metabolic model o ...... terologous protein production.
@en
Genome-scale metabolic model o ...... terologous protein production.
@nl
type
label
Genome-scale metabolic model o ...... terologous protein production.
@en
Genome-scale metabolic model o ...... terologous protein production.
@nl
prefLabel
Genome-scale metabolic model o ...... terologous protein production.
@en
Genome-scale metabolic model o ...... terologous protein production.
@nl
P2093
P2860
P50
P356
P1476
Genome-scale metabolic model o ...... eterologous protein production
@en
P2093
Michael Maurer
Seung Bum Sohn
Tae Yong Kim
P2860
P304
P356
10.1002/BIOT.201000078
P577
2010-07-01T00:00:00Z