Total synthesis of syringolin A and improvement of its biological activity.
about
Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death.Substrate-guided optimization of the syringolins yields potent proteasome inhibitors with activity against leukemia cell lines.Impact of the structures of macrocyclic Michael acceptors on covalent proteasome inhibition.Immunoproteasome inhibition and bioactivity of thiasyrbactins.Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits.
P2860
Total synthesis of syringolin A and improvement of its biological activity.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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name
Total synthesis of syringolin A and improvement of its biological activity.
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Total synthesis of syringolin A and improvement of its biological activity.
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type
label
Total synthesis of syringolin A and improvement of its biological activity.
@en
Total synthesis of syringolin A and improvement of its biological activity.
@nl
prefLabel
Total synthesis of syringolin A and improvement of its biological activity.
@en
Total synthesis of syringolin A and improvement of its biological activity.
@nl
P2093
P2860
P356
P1476
Total synthesis of syringolin A and improvement of its biological activity.
@en
P2093
Akira Matsuda
Hidetaka Hosono
Hiroshi Takeda
Koji Nakagawa
Masahiro Asaka
Satoshi Ichikawa
Takuya Chiba
P2860
P304
P356
10.1002/ANIE.201402428
P407
P577
2014-03-25T00:00:00Z