Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.
about
MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cellsSynaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2Alternative cyclin D1 splice forms differentially regulate the DNA damage responseMolecular pathogenesis and clinical management of Fanconi anemiaSuppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapyHow the fanconi anemia pathway guards the genomeCheckpoint signaling from a single DNA interstrand crosslinkHDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombinationThe Fanconi anemia pathway and DNA interstrand cross-link repairFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairFormaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessmentSimultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesionsXpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideumReplication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts.The role of Bcl-x(L) protein in nucleotide excision repair-facilitated cell protection against cisplatin-induced apoptosis.A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants.DNA interstrand crosslink repair in mammalian cells: step by step.Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agentsThe epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.The multifunctional SNM1 gene family: not just nucleasesRAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network.REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility.Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesisHuman Mus81 and FANCB independently contribute to repair of DNA damage during replication.DNA polymerase zeta (pol zeta) in higher eukaryotes.Mechanism of replication-coupled DNA interstrand crosslink repair.REV3L, a promising target in regulating the chemosensitivity of cervical cancer cells.Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases.The mTOR inhibitor rapamycin suppresses DNA double-strand break repairIdentification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines.RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib.Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity.Calreticulin expression in the clonal plasma cells of patients with systemic light-chain (AL-) amyloidosis is associated with response to high-dose melphalan.
P2860
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P2860
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Multiple repair pathways media ...... ng agents in vertebrate cells.
@en
Multiple repair pathways media ...... ng agents in vertebrate cells.
@nl
type
label
Multiple repair pathways media ...... ng agents in vertebrate cells.
@en
Multiple repair pathways media ...... ng agents in vertebrate cells.
@nl
prefLabel
Multiple repair pathways media ...... ng agents in vertebrate cells.
@en
Multiple repair pathways media ...... ng agents in vertebrate cells.
@nl
P2093
P50
P1433
P1476
Multiple repair pathways media ...... ng agents in vertebrate cells.
@en
P2093
Brian J Orelli
Douglas K Bishop
Eiichiro Sonoda
Hiroshi Arakawa
Jean-Marie Buerstedde
Jun A Takahashi
Kasumi Araki
Kazuhiko Yamamoto
Kuniharu Nojima
Masamichi Ishiai
P304
11704-11711
P356
10.1158/0008-5472.CAN-05-1214
P407
P577
2005-12-01T00:00:00Z