Molecular pathogenesis and clinical management of Fanconi anemia
about
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairHow SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair PathwayDisease-causing missense mutations in human DNA helicase disordersThe inherited bone marrow failure syndromesCohesinopathies of a feather flock togetherFanconi anemia and the cell cycle: new perspectives on aneuploidySmall-molecule inhibitors of the Myc oncoproteinA novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51PALB2: the hub of a network of tumor suppressors involved in DNA damage responsesOverexpression of Rad51C splice variants in colorectal tumorsCan Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant RadioprotectorsAluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.Genetic predisposition syndromes: when should they be considered in the work-up of MDS?Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.Male fertility defect associated with disrupted BRCA1-PALB2 interaction in miceThe Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemiaTargeting aldehyde dehydrogenase 2: new therapeutic opportunities.Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancerFANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCLGlobal and disease-associated genetic variation in the human Fanconi anemia gene family.Damaged mitochondria in Fanconi anemia - an isolated event or a general phenomenon?Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Fancd2 is required for nuclear retention of Foxo3a in hematopoietic stem cell maintenance.Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.DNA-damage foci to detect and characterize DNA repair alterations in children treated for pediatric malignanciesTranscriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver.RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer familiesCharacterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroupLow Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within MinutesDNA helicases involved in DNA repair and their roles in cancerFANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription.Identification of point mutations and large intragenic deletions in Fanconi anemia using next-generation sequencing technologyLoss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt Signaling Pathway.SCO2 Mediates Oxidative Stress-Induced Glycolysis to Oxidative Phosphorylation Switch in Hematopoietic Stem CellsRad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo.
P2860
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P2860
Molecular pathogenesis and clinical management of Fanconi anemia
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular pathogenesis and clinical management of Fanconi anemia
@ast
Molecular pathogenesis and clinical management of Fanconi anemia
@en
Molecular pathogenesis and clinical management of Fanconi anemia
@nl
type
label
Molecular pathogenesis and clinical management of Fanconi anemia
@ast
Molecular pathogenesis and clinical management of Fanconi anemia
@en
Molecular pathogenesis and clinical management of Fanconi anemia
@nl
prefLabel
Molecular pathogenesis and clinical management of Fanconi anemia
@ast
Molecular pathogenesis and clinical management of Fanconi anemia
@en
Molecular pathogenesis and clinical management of Fanconi anemia
@nl
P2860
P3181
P356
P1476
Molecular pathogenesis and clinical management of Fanconi anemia
@en
P2093
Alan D D'Andrea
Younghoon Kee
P2860
P304
P3181
P356
10.1172/JCI58321
P407
P577
2012-11-01T00:00:00Z