about
The Response of Macrophages and Neutrophils to Hypoxia in the Context of Cancer and Other Inflammatory DiseasesUnstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-EHypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaBA novel role for the hypoxia inducible transcription factor HIF-1alpha: critical regulation of inflammatory cell function.Dual mechanism of vascular endothelial growth factor upregulation by hypoxia in human hepatocellular carcinomaThe return of metabolism: biochemistry and physiology of the pentose phosphate pathwayHypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity.2-methoxyestradiol inhibits hypoxia-inducible factor-1{alpha} and suppresses growth of lesions in a mouse model of endometriosis.Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways.The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.Application of two-dimensional gel-based mass spectrometry to functionally dissect resistance to targeted cancer therapy.Antineoplastic activity of 2-methoxyestradiol in human pancreatic and gastric cancer cells with different multidrug-resistant phenotypes.Vascular endothelial growth factor in articular cartilage of healthy and osteoarthritic human knee joints.Hypoxia and HIF-1alpha in osteoarthritis.Cholangiocarcinoma, gone without the Wnt?Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DHIF-1alpha expression regulates the bactericidal capacity of phagocytes.Pigment epithelium derived factor--the product of the EPC-1 gene--is expressed by articular chondrocytes and up regulated in osteoarthritis.Neuroendocrine-specific and gastrin-dependent expression of a chromogranin A-luciferase fusion gene in transgenic mice.Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors.Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer.Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent.Hepatocyte growth factor and c-Met expression in rat and human liver fibrosis.Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.Time course of contrast enhancement by micro-CT with dedicated contrast agents in normal mice and mice with hepatocellular carcinoma: comparison of one iodinated and two nanoparticle-based agents.HIFs as central regulators of gastric cancer pathogenesis.Gastrin transactivates the chromogranin A gene through MEK-1/ERK- and PKC-dependent phosphorylation of Sp1 and CREB.Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3.Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis.De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop.A microfluidics platform for combinatorial drug screening on cancer biopsies.Hypoxia reduces and redirects selenoprotein biosynthesisRapid identification of optimal drug combinations for personalized cancer therapy using microfluidicsTransforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cellsHepatocyte growth factor in human osteoarthritic cartilageHepatocytes as a source of collagen type XVIII endostatinImpact of microvessel density on lymph node metastasis and survival after curative resection of pancreatic cancerPatient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies
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P50
description
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wetenschapper
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հետազոտող
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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Thorsten Cramer
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P106
P31
P496
0000-0002-6462-239X