Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module. - Test2 - elhamkhani - TriplyDB

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module.

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module.

http://www.wikidata.org/entity/Q53424743

about

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation Mechanical regulation of T-cell functions Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier.Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion A Pan-GTPase Inhibitor as a Molecular Probe Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling.Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin.PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells.Critical roles for Rac GTPases in T-cell migration to and within lymph nodes.Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation Unsupervised explorative data analysis of normal human leukocytes and BCR/ABL positive leukemic cells mid-infrared spectra.Chemokine arrest signals to leukocyte integrins trigger bi-directional-occupancy of individual heterodimers by extracellular and cytoplasmic ligands Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.Rac1 selective activation improves retina ganglion cell survival and regeneration Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation.Regulation of integrin affinity on cell surfaces The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo.JAK2 tyrosine kinase mediates integrin activation induced by CXCL12 in B-cell chronic lymphocytic leukemia TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA An Emerging Role for PI5P in T Cell Biology.Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activation Rho family GTPases and their regulators in lymphocytes.Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrier SHARPIN regulates uropod detachment in migrating lymphocytes.Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.Rolling cell adhesion α5β1 integrin induces the expression of noncartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers.The insider's guide to leukocyte integrin signalling and function.Leukocyte integrin activation and deactivation: novel mechanisms of balancing inflammation.Neutrophil arrest by LFA-1 activation The multifaceted role of PIP2 in leukocyte biology.On the potential involvement of CD11d in co-stimulating the production of interferon-γ by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3.Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1 Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity.RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones.

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P2860

Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module.

http://www.wikidata.org/entity/Q53424743

description

2009 nî lūn-bûn

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Regulation of conformer-specif ...... riggered Rho signaling module.

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Nature Immunology

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Regulation of conformer-specif ...... triggered Rho signaling module

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Alessio Montresor

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Barbara Rossi

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Carlo Laudanna

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Cinzia Giagulli

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Donald Staunton

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Gabriela Constantin

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Matteo Bolomini-Vittori

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P2860

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

Structural basis of integrin activation by talin

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

Determination of interaction sites of phospholipase D1 for RhoA

The origins and evolution of functional modules: lessons from protein complexes

Rho GTPases and the actin cytoskeleton

Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

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185-194

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10.1038/NI.1691

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2

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10

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Marianna Martinello

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23771210

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19136961

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