Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton.
about
Regulation of c-Src by binding to the PDZ domain of AF-6Specificity in Ras and Rap signalingComputer simulations of cell sorting due to differential adhesionConcomitant binding of Afadin to LGN and F-actin directs planar spindle orientationEpithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.Afadin controls cadherin cluster stability using clathrin-independent mechanism.Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition.Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton.Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.Under construction: building the macromolecular superstructure and signaling components of an electrical synapse.Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.PHF10 is required for cell proliferation in normal and SV40-immortalized human fibroblast cellsJunctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration.The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration.Cooperative role of nectin-nectin and nectin-afadin interactions in formation of nectin-based cell-cell adhesion.Loss of AF6/afadin, a marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth.Role of AF6 protein in cell-to-cell spread of Herpes simplex virus 1.A genome-wide functional screen shows MAGI-1 is an L1CAM-dependent stabilizer of apical junctions in C. elegans.s-Afadin binds more preferentially to the cell adhesion molecules nectins than l-afadin.
P2860
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P2860
Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@en
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@nl
type
label
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@en
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@nl
prefLabel
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@en
Regulation of epithelial wound ...... f AF6 with actin cytoskeleton.
@nl
P921
P356
P1476
Regulation of epithelial wound ...... of AF6 with actin cytoskeleton
@en
P2093
Karin Moelling
P304
P356
10.1242/JCS.03027
P407
P577
2006-08-01T00:00:00Z