about
sameAs
1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)Design of O -Acetylserine Sulfhydrylase Inhibitors by Mimicking NatureIdentification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolutionBiological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agentIdentification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalisBound water at protein-protein interfaces: partners, roles and hydrophobic bubbles as a conserved motif3d interaction homology: The structurally known rotamers of tyrosine derive from a surprisingly limited set of information-rich hydropathic interaction environments described by maps.The Roles of Water in the Protein Matrix: A Largely Untapped Resource for Drug Discovery.Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98Which aminoglycoside ring is most important for binding? A hydropathic analysis of gentamicin, paromomycin, and analogues.Energetics of the protein-DNA-water interaction.Novel inhibitors of anthrax edema factor.Paramyxovirus receptor-binding molecules: engagement of one site on the hemagglutinin-neuraminidase protein modulates activity at the second site.On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different.Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL.Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic targetMolecular basis of E. coli L-threonine aldolase catalytic inactivation at low pH.Inhibition of hendra virus fusion.Targeting cystalysin, a virulence factor of treponema denticola-supported periodontitis.Predicting the molecular interactions of CRIP1a-cannabinoid 1 receptor with integrated molecular modeling approachesDesign, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligandsPremature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machineryA second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanism.Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based DesignDocking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity.Tyrosine nitration of IkappaBalpha: a novel mechanism for NF-kappaB activation.Target flexibility: an emerging consideration in drug discovery and design.Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mCorrect protonation states and relevant waters = better computational simulations?Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities.Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).Structure-activity relationships of retro-dihydrochalcones isolated from Tacca sp.3,5-Disubstituted-thiazolidine-2,4-dione analogs as anticancer agents: design, synthesis and biological characterization.Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation.Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activityStructure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors.Hydropathic analysis of the free energy differences in anthracycline antibiotic binding to DNADesign, synthesis and biological evaluation of novel stilbene-based antitumor agents.Development of water soluble derivatives of cis-3, 4', 5-trimethoxy-3'-aminostilbene for optimization and use in cancer therapy.Comparative docking study of anibamine as the first natural product CCR5 antagonist in CCR5 homology models.
P50
Q24564306-76A62F8D-DF30-4ABE-AF64-72D94621B1A3Q27658287-E9AF8061-46BC-4AE3-A026-98454906B746Q27676158-BA04F063-B86B-4CCF-9439-753B4B60EB04Q28486289-3B267309-6350-49F4-AF60-7B4D27EC2C0FQ28550756-DDCB4847-A36E-4CED-B286-6AF4811460A8Q28744655-440BCB5B-1FE1-4A4B-9408-224EAD464F7EQ30374011-F781A7F7-C60C-44BA-BC90-0E47CCD8008EQ30401696-066ADEEC-75B3-46E4-BBAE-89853D9983B9Q30514072-2CFCE7A4-42B6-436E-BAD2-01C64587F57BQ32020293-C27C943E-F864-497E-A84C-4BC800EC2E19Q33268780-726C8ECD-3542-4A4C-A2AE-8F873F19DBACQ33351165-B6A15556-37A0-4118-9D2F-548CB43F7EBAQ34302118-A45C4B17-CF6A-4D89-9906-B7A808EAC758Q34477404-0016C26E-BABB-45BA-82F4-E040F95DFA9CQ34902453-DBDAD954-D554-4C9B-9A7C-7ABEAB7C4866Q35027753-F847BAE4-E351-4F75-80BB-DBDED1F71CDAQ35070004-0CDC3BEF-927F-495E-8AE7-27F7712AE69EQ35101317-B4FC2EDE-75A2-4595-A147-39721122EC12Q35116929-458BD341-A6E1-41AA-BFC8-23D8D8A3CE65Q35159050-6B05862C-3599-4FAB-8C9C-8780E710AF68Q35236118-C60BB84E-FCBB-4124-8343-13898D0616DFQ35515383-61D6B903-18E9-4539-8B00-2B822C8F879CQ35785169-85740529-19C4-4610-BF14-DE19233382E8Q36502953-EDEE1C3E-0B76-48CD-AF5C-10D685AA44C5Q36617205-3C7D8EE5-60E9-455F-A379-C9097A3DA85FQ37183903-86FDBA13-0B5A-4EDF-9D92-90A1B80EDA68Q37240137-2A5E8E8E-6593-4F59-9C51-593FAA940294Q37317909-C47D6534-0DF8-468E-BE96-77F8737ADC28Q38061456-A0C268EE-92E5-4887-AF00-BD313626BD2DQ38706459-E8EA21BF-9C65-441A-B04C-4D79E5101B5EQ38772484-F96CABEA-4FE8-4909-884C-0F25FA1CA74CQ39314911-70A70BEB-ED02-4DD3-A9C9-D62CE465E009Q39444900-A922C28E-C82B-493E-9AE7-87883FBBFF31Q39700690-06FA8356-5290-477E-A71C-1B106E20A6E4Q39775098-F9CC2865-BCA2-4074-8DB3-E096627A44B9Q39792692-BF0B1DCC-21BD-4E16-9598-178A394111DBQ39808730-A513C478-8E2D-4A80-A286-8C2893A1AB2DQ39899728-16CCDD9A-2972-44DE-92F0-0F1C4682F30BQ39976481-89B427C9-AB28-4C83-8C43-887DB71F2FBDQ40007908-CC47730E-BE28-48AC-BCB9-D6CE1A3B5746
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Glen E. Kellogg
@ast
Glen E. Kellogg
@en
Glen E. Kellogg
@es
Glen E. Kellogg
@nl
Glen E. Kellogg
@sl
type
label
Glen E. Kellogg
@ast
Glen E. Kellogg
@en
Glen E. Kellogg
@es
Glen E. Kellogg
@nl
Glen E. Kellogg
@sl
prefLabel
Glen E. Kellogg
@ast
Glen E. Kellogg
@en
Glen E. Kellogg
@es
Glen E. Kellogg
@nl
Glen E. Kellogg
@sl
P106
P1153
7006505039
P2456
P31
P496
0000-0002-6282-6794