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Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific bindingCrystal structure of the human receptor activity-modifying protein 1 extracellular domainCatalytic roles for two water bridged residues (Asp-98 and His-255) in the active site of copper-containing nitrite reductaseCrystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentationStructural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPasesDirect inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free stateCell-permeable Carboxyl-terminal p27Kip1 Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 KinaseIdentification of Critical Residues in G 13 for Stimulation of p115RhoGEF Activity and the Structure of the G 13-p115RhoGEF Regulator of G Protein Signaling Homology (RH) Domain ComplexCrystal Structure of the Ca2+/Calmodulin-dependent Protein Kinase Kinase in Complex with the Inhibitor STO-609Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited formsStructural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptorDOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.Structural basis of interleukin-5 dimer recognition by its α receptorLysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modesSite-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differencesThe crystal structure of mouse Nup35 reveals atypical RNP motifs and novel homodimerization of the RRM domainCrystal structure of the RUN domain of the RAP2-interacting protein xBlockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3.Crystal structure of an enhancer of rudimentary homolog (ERH) at 2.1 Angstroms resolution.Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution.Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factorsTNIK inhibition abrogates colorectal cancer stemnessImmune regulatory functions of DOCK family proteins in health and disease.X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction.Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities.Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5.Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8.Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors.Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody-antigen interaction.Structure of the UNC5H2 death domain.Identification of novel drug-resistant EGFR mutant inhibitors by in silico screening using comprehensive assessments of protein structures.Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysisCholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Mutsuko Kukimoto-Niino
@ast
Mutsuko Kukimoto-Niino
@en
Mutsuko Kukimoto-Niino
@es
Mutsuko Kukimoto-Niino
@nl
type
label
Mutsuko Kukimoto-Niino
@ast
Mutsuko Kukimoto-Niino
@en
Mutsuko Kukimoto-Niino
@es
Mutsuko Kukimoto-Niino
@nl
prefLabel
Mutsuko Kukimoto-Niino
@ast
Mutsuko Kukimoto-Niino
@en
Mutsuko Kukimoto-Niino
@es
Mutsuko Kukimoto-Niino
@nl
P106
P31
P496
0000-0002-4178-1611