about
A unique set of SH3-SH3 interactions controls IB1 homodimerization.The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1)Role of microRNAs in islet beta-cell compensation and failure during diabetesReduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particlesMicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cellsComplexin I regulates glucose-induced secretion in pancreatic beta-cellsEndoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDLExpression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells.JNK3 is required for the cytoprotective effect of exendin 4ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis.The class I histone deacetylase inhibitor MS-275 prevents pancreatic beta cell death induced by palmitate.Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.Transdermal skin patch based on reduced graphene oxide: A new approach for photothermal triggered permeation of ondansetron across porcine skin.MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.Islet Brain 1 Protects Insulin Producing Cells against LipotoxicityEvidence for tuning adipocytes ICER levels for obesity care.Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction.Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte functionPotentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin.Decompensation of β-cells in diabetes: when pancreatic β-cells are on ICE(R).LEDGF/p75 TATA-less promoter is driven by the transcription factor Sp1.KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.Neurotensin is a regulator of insulin secretion in pancreatic beta-cells.Role of the transcriptional factor C/EBPbeta in free fatty acid-elicited beta-cell failure.Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells.Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion.Neuronal traits are required for glucose-induced insulin secretion.Compensatory mechanisms of pancreatic beta cells: insights into the therapeutic perspectives for diabetes.Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells.Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study.Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis.Loss-of-function mutations in ADCY3 cause monogenic severe obesity.The hairy and enhancer of split 1 is a negative regulator of the repressor element silencer transcription factor.Photothermally triggered on-demand insulin release from reduced graphene oxide modified hydrogels.Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode.Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity Associated Type 2 Diabetes.
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
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type
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Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
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Amar Abderrahmani
@en
Amar Abderrahmani
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Amar Abderrahmani
@nl
P106
P31
P496
0000-0003-0752-0343