Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.
about
Glucagon and heart in type 2 diabetes: new perspectivesCarbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1Sodium-glucose co-transporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors combination therapy in type 2 diabetes: A systematic review of current evidenceSodium-glucose cotransporter-2 inhibitor combination therapy to optimize glycemic control and tolerability in patients with type 2 diabetes: focus on dapagliflozin-metforminSodium-glucose cotransporter 2 inhibition: cardioprotection by treating diabetes-a translational viewpoint explaining its potential salutary effectsSGLT2 Inhibitors May Predispose to KetoacidosisThe Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart FailureNiclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetesInfluence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over TimeAntidiabetic effects of Brucea javanica seeds in type 2 diabetic ratsPharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus.Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations.CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells.Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.Sodium-glucose cotransporter-2 inhibition and acidosis in patients with type 2 diabetes: a review of US FDA data and possible conclusionsMetabolic and hemodynamic effects of sodium-dependent glucose cotransporter 2 inhibitors on cardio-renal protection in the treatment of patients with type 2 diabetes mellitusEmpagliflozin in the treatment of type 2 diabetes: evidence to dateSGLT-2 inhibition and glucagon: Cause for alarm?Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 SecretionThe Effects of Empagliflozin, an SGLT2 Inhibitor, on Pancreatic β-Cell Mass and Glucose Homeostasis in Type 1 DiabetesIpragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction.Diabetic Ketoacidosis and Related Events in the Canagliflozin Type 2 Diabetes Clinical Program.Possible Increase in Serum FABP4 Level Despite Adiposity Reduction by Canagliflozin, an SGLT2 Inhibitor.Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic MiceRenal sodium-glucose cotransporter inhibition in the management of type 2 diabetes mellitusSodium-glucose co-transporter-2 inhibitors and euglycemic ketoacidosis: Wisdom of hindsight.Sodium glucose cotransporter 2 inhibition in the diabetic kidney: an updateEffect of Dapagliflozin With and Without Acipimox on Insulin Sensitivity and Insulin Secretion in T2DM Males.SGLT2 Inhibitors and Cardiovascular Risk: Lessons Learned From the EMPA-REG OUTCOME Study.Euglycemic Diabetic Ketoacidosis in a 27 year-old female patient with type-1-Diabetes treated with sodium-glucose cotransporter-2 (SGLT2) inhibitor Canagliflozin.Substantial Effects of Luseogliflozin Revealed by Analyzing Responses to Postprandial Hyperglycemia: Post Hoc Subanalyses of a Randomized Controlled StudyChanges in Levels of Biomarkers Associated with Adipocyte Function and Insulin and Glucagon Kinetics During Treatment with Dapagliflozin Among Obese Type 2 Diabetes Mellitus Patients.Quality measure attainment with dapagliflozin plus metformin extended-release as initial combination therapy in patients with type 2 diabetes: a post hoc pooled analysis of two clinical studiesThe renal effects of SGLT2 inhibitors and a mini-review of the literature.The Effect of Tofogliflozin Treatment on Postprandial Glucose and Lipid Metabolism in Japanese Men With Type 2 Diabetes: A Pilot Study.A comprehensive review of the pharmacodynamics of the SGLT2 inhibitor empagliflozin in animals and humans.The treatment of type 1 diabetes mellitus with agents approved for type 2 diabetes mellitus.Is it time to think about the sodium glucose co-transporter 2 sympathetically?Energy balance and metabolic changes with sodium-glucose co-transporter 2 inhibition.Sodium-Glucose Cotransporter 2 Inhibitors in the Treatment of Type 2 Diabetes Mellitus.
P2860
Q26738580-BDA5058A-959E-4C67-A796-8E07328DB899Q26749211-16AEE481-210D-4566-A316-26A480138911Q26752703-E42EFE40-26FF-49B7-B42C-75B5BB8515F4Q26752815-C5E8A5CF-8C09-4E50-AA43-9138CF4588C5Q28072765-CB84F9A9-F63A-4A52-BD5A-BCB93312E1CCQ28081173-29F4F8EE-0CF5-4D08-9B0D-3E6218602BC6Q28082343-2DF3A0B7-927D-442A-A565-10FF22AB76A5Q28359714-568E5B4A-F3FE-4DC8-841B-11734FE99CF3Q28552106-478DE03C-7CEF-4A78-A326-34F91A7D9207Q28817360-1D35A0F5-3840-426C-A1BE-08B47E42C785Q30249371-959A33ED-9C0A-4835-B617-29699135F405Q33638177-966CA56F-D590-4BD1-8753-56746859EB8EQ33671461-91844E80-6EEE-40AA-B31F-ADA71569C609Q33726555-ACC7F96E-C6AA-44FC-AA0E-CD71F026D901Q33820904-7880AA77-4615-43AD-8D8E-BA1A37B48153Q33871321-40302746-9FB7-4C08-A2BC-3DDBA2B89503Q34502358-4750DF81-29D8-42BA-AD3E-A3080B108D17Q35812506-E41892C1-2E02-4BC8-A9CB-92A2B14E5098Q35858749-5CF82F13-8FEC-4664-91E7-4F8D2A5D9B66Q35903101-B848CEC9-D2D4-4223-AD1C-2D5F78250836Q35957448-1FC62D5C-2A17-404A-AADB-765B07A10B62Q35973246-68FF5864-DC6A-4855-9259-4D5CCBE02C35Q36001903-BAB74ADE-CA7E-43AE-815E-B705932B2E53Q36057947-58C5C143-2923-46E3-91AF-318F9704EF9CQ36345951-FFE292C2-7A72-4200-9AD9-AFF7AE3504AEQ36357997-28049C10-278D-4320-BC89-ACE51B0C1C63Q36435496-07327DC6-6DF6-4303-A5E3-6539B71BA604Q36716030-63391C9E-1889-4364-B92E-0256FF9FC562Q36820604-51478AA9-AD4A-4A8F-ABE0-02BBF9D5CFECQ37055206-257AEBA5-1091-4CDD-A381-A5C90128997BQ37080615-81C370D7-5473-46E2-BEB0-498613184BE2Q37302700-6D8FC434-BF88-41F2-BDF1-D2C0050B1677Q37354187-A8C20244-2FFB-4FC2-A9C7-31778A2753E6Q37632127-1CE7EF98-8C31-4859-9912-448BB653D1DDQ37737187-75C42670-BEF2-43C7-83A3-CCF7AF082CF3Q38537119-3D19B9E3-B495-42AF-95E9-48C61DF542F8Q38580783-21FFC878-F916-4889-8B34-F9CCCD2E8723Q38586588-8ED2592E-C954-453B-8B09-481C64145165Q38592327-64189EE1-475C-49D0-83B8-225108DED3A0Q38602771-0E220CEB-84AB-42F5-9B7E-6CD4258565F5
P2860
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh-hant
name
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@en
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@nl
type
label
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@en
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@nl
prefLabel
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@en
Inhibition of the glucose tran ...... s triggers glucagon secretion.
@nl
P2093
P2860
P50
P356
P1433
P1476
Inhibition of the glucose tran ...... ls triggers glucagon secretion
@en
P2093
Abdullah Sener
Cédric Beaucamps
Ericka Moerman
Gurvan Queniat
Iuliana Popescu
Julie Kerr-Conte
Nathalie Delalleau
Valéry Gmyr
Willy J Malaisse
P2860
P2888
P304
P356
10.1038/NM.3828
P407
P577
2015-04-20T00:00:00Z