Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code
about
Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloningNucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factorsZinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsSequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Krüppel-associated box proteinZinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleasesTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesA rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoterRapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modificationA bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactionsConservation and evolution of cis-regulatory systems in ascomycete fungiAb initio prediction of transcription factor targets using structural knowledge.Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein.Combining SELEX with quantitative assays to rapidly obtain accurate models of protein-DNA interactions.Genome-editing Technologies for Gene and Cell TherapyOrigins of Programmable Nucleases for Genome EngineeringRevealing off-target cleavage specificities of zinc-finger nucleases by in vitro selectionExtensive protein and DNA backbone sampling improves structure-based specificity prediction for C2H2 zinc fingers.Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based methodRapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions.Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arraysProbing the DNA-binding affinity and specificity of designed zinc finger proteinsStimulation of homologous recombination through targeted cleavage by chimeric nucleases.Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay.Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish.Custom-designed zinc finger nucleases: what is next?Manipulating the mammalian genome by homologous recombinationGlobal analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applicationsAdditivity in protein-DNA interactions: how good an approximation is it?Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants.A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.The multifunctional role of EKLF/KLF1 during erythropoiesis.Recognition models to predict DNA-binding specificities of homeodomain proteins.Epigenetic manipulation of gene expression: a toolkit for cell biologistsAn information transmission model for transcription factor binding at regulatory DNA sites.TALENs: a widely applicable technology for targeted genome editing.Knockout punches with a fistful of zinc fingers.Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast.Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases.
P2860
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P2860
Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code
description
article
@en
im Februar 1999 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 1999
@uk
name
Analysis of zinc fingers optim ...... utility of a recognition code
@en
Analysis of zinc fingers optim ...... utility of a recognition code
@nl
type
label
Analysis of zinc fingers optim ...... utility of a recognition code
@en
Analysis of zinc fingers optim ...... utility of a recognition code
@nl
prefLabel
Analysis of zinc fingers optim ...... utility of a recognition code
@en
Analysis of zinc fingers optim ...... utility of a recognition code
@nl
P2093
P356
P1476
Analysis of zinc fingers optim ...... utility of a recognition code
@en
P2093
P304
P356
10.1006/JMBI.1998.2421
P407
P577
1999-02-01T00:00:00Z