about
Evolution of minimal specificity and promiscuity in steroid hormone receptorsProtein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestorDetecting High-Order Epistasis in Nonlinear Genotype-Phenotype MapsHistorical contingency and its biophysical basis in glucocorticoid receptor evolution.How sequence defines structure: a crystallographic map of DNA structure and conformation.Evolutionary biochemistry: revealing the historical and physical causes of protein properties.Thermodynamic system drift in protein evolution.The thermostability and specificity of ancient proteins.Evolutionary trend toward kinetic stability in the folding trajectory of RNases H.Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.High-order epistasis shapes evolutionary trajectories.Resurrection of an Urbilaterian U1A/U2B″/SNF proteinConservation of specificity in two low-specificity proteins.Molecular ensembles make evolution unpredictable.Human S100A5 binds Ca2+ and Cu2+ independently.Robustness of Reconstructed Ancestral Protein Functions to Statistical Uncertainty.Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide.pytc: Open-Source Python Software for Global Analyses of Isothermal Titration Calorimetry Data.pytc: a python package for analysis of Isothermal Titration Calorimetry experimentsEnzymes emerge by upcyclingEvolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9Tracing the evolution of novel features of human Toll-like receptor 4
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-0241-4122
@en
name
Michael J Harms
@ast
Michael J Harms
@en
Michael J Harms
@es
Michael J Harms
@nl
type
label
Michael J Harms
@ast
Michael J Harms
@en
Michael J Harms
@es
Michael J Harms
@nl
prefLabel
Michael J Harms
@ast
Michael J Harms
@en
Michael J Harms
@es
Michael J Harms
@nl
P106
P31
P496
0000-0002-0241-4122