Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
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Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential.Beta-cell CaV channel regulation in physiology and pathophysiology.Mechanisms of inhibition of insulin release.The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretionImportant role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulinRegulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.Quarternary structure and enzymological properties of the different hormone-sensitive lipase (HSL) isoforms.The neuronal K+Cl- co-transporter 2 (Slc12a5) modulates insulin secretion.Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmittersA reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.An IP3R3- and NPY-expressing microvillous cell mediates tissue homeostasis and regeneration in the mouse olfactory epitheliumA reassessment of the modulatory role of cyclic AMP in catecholamine secretion by chromaffin cells.Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells.An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells.Protein kinase A takes center stage in ATP-dependent insulin secretionDifferential regulation of granule-to-granule and granule-to-plasma membrane fusion during secretion from rat pituitary lactotrophs.A highly Ca2+-sensitive pool of granules is regulated by glucose and protein kinases in insulin-secreting INS-1 cellsProtein kinase activation increases insulin secretion by sensitizing the secretory machinery to Ca2+.Hepatic adenylate cyclase 3 is upregulated by Liraglutide and subsequently plays a protective role in insulin resistance and obesity.CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensorMechanisms of insulin secretion in malnutrition: modulation by amino acids in rodent models.Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.Beta cell connectivity in pancreatic islets: a type 2 diabetes target?PREB regulates transcription of pancreatic glucokinase in response to glucose and cAMP.Vitamin D and pancreas: The role of sunshine vitamin in the pathogenesis of diabetes mellitus and pancreatic cancer.Local and regional control of calcium dynamics in the pancreatic islet.Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in mouse beta-cells.The mechanisms of cell membrane resealing in rabbit corneal epithelial cells.Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion.Regulation of antiprotease and antimicrobial protein secretion by airway submucosal gland serous cells.Amplification of exocytosis by Ca2+-induced Ca2+ release in INS-1 pancreatic beta cells.Luminal CCK-releasing factor stimulates CCK release from human intestinal endocrine and STC-1 cells.Secretagogue-dependent phosphorylation of the insulin granule membrane protein phogrin is mediated by cAMP-dependent protein kinase.The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion.Protein kinase A inhibition and PACAP-induced insulin secretion in HIT-T15 cells.Insulin secretagogues activate the secretory granule receptor-like protein-tyrosine phosphatase IAR.Evidence for contribution by increased cytoplasmic Na+ to the insulinotropic action of PACAP38 in HIT-T15 cells.
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P2860
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в травні 1993
@uk
name
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@en
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@nl
type
label
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@en
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@nl
prefLabel
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@en
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
@nl
P356
P1433
P1476
Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells
@en
P2093
F M Ashcroft
P2888
P304
P356
10.1038/363356A0
P407
P577
1993-05-01T00:00:00Z
P6179
1050252572