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Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sitesHow to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylaseFrom lin-benzoguanines to lin-benzohypoxanthines as ligands for Zymomonas mobilis tRNA-guanine transglycosylase: replacement of protein-ligand hydrogen bonding by importing water clustersOrigins of stereoselectivities of dihydroxylations of cis-bicyclo[3.3.0]octenesHigh-affinity inhibitors of tRNA-guanine transglycosylase replacing the function of a structural water cluster.Total Synthesis of (-)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade.Synthesis of 2,4,5-Trisubstituted Thiazoles with a 5-(N,N-Dimethylaminomethyl) SubstituentHigh-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization
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description
researcher ORCID ID = 0000-0002-2424-9527
@en
wetenschapper
@nl
name
Philipp C Kohler
@ast
Philipp C Kohler
@en
Philipp C Kohler
@nl
type
label
Philipp C Kohler
@ast
Philipp C Kohler
@en
Philipp C Kohler
@nl
prefLabel
Philipp C Kohler
@ast
Philipp C Kohler
@en
Philipp C Kohler
@nl
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P31
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0000-0002-2424-9527