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Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI miceRestoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusionProteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challengeGliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease.ApoE isoform-specific regulation of regeneration in the peripheral nervous systemRegionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype.Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementiaThe subtype of GluN2 C-terminal domain determines the response to excitotoxic insults.Synaptic NMDA receptor activity boosts intrinsic antioxidant defensesEffects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.Axon-glial disruption: the link between vascular disease and Alzheimer's disease?Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning.Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice.Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic ratsGradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory.Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion.Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse.Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease.Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia.Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion.4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia.Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice.Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury.Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia.Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge.White matter degeneration in vascular and other ageing-related dementias.Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease.Mild fluid percussion injury in mice produces evolving selective axonal pathology and cognitive deficits relevant to human brain injury.Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum.Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis.Apolipoprotein E and the CNS response to injury.APOE epsilon3 gene transfer attenuates brain damage after experimental stroke.White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion.Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology.Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat.
P50
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P50
description
researcher ORCID ID = 0000-0002-9620-3691
@en
wetenschapper
@nl
name
Karen Horsburgh
@ast
Karen Horsburgh
@en
Karen Horsburgh
@es
Karen Horsburgh
@nl
type
label
Karen Horsburgh
@ast
Karen Horsburgh
@en
Karen Horsburgh
@es
Karen Horsburgh
@nl
prefLabel
Karen Horsburgh
@ast
Karen Horsburgh
@en
Karen Horsburgh
@es
Karen Horsburgh
@nl
P106
P21
P31
P496
0000-0002-9620-3691