about
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsCrif1 is a novel transcriptional coactivator of STAT3Lgr5 homologues associate with Wnt receptors and mediate R-spondin signallingModeling mouse and human development using organoid culturesGeneration of BAC transgenic epithelial organoidsDifferentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epitheliumFunctional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patientsNeuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1A crucial role of WW45 in developing epithelial tissues in the mouseSnx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafishMind bomb 1 is essential for generating functional Notch ligands to activate NotchMind bomb-2 is an E3 ligase for Notch ligandThe WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells.An obligatory role of mind bomb-1 in notch signaling of mammalian developmentMind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.Controlled gene expression in primary Lgr5 organoid cultures.The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markersReceptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal developmentSurvival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling.Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.A video protocol of retroviral infection in primary intestinal organoid cultureMind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell developmentInactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.Stem cells marked by the R-spondin receptor LGR5.Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells.Adult stem cell lineage tracing and deep tissue imaging.One-step generation of conditional and reversible gene knockouts.Clonal Evolution of Stem Cells in the Gastrointestinal Tract.Adult gastric stem cells and their niches.Stem Cells in Repair of Gastrointestinal Epithelia.Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells.A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemerLong-term, hormone-responsive organoid cultures of human endometrium in a chemically defined mediumA critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.Retroviral gene expression control in primary organoid cultures.Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids.Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-4134-8033
@en
name
Bon-Kyoung Koo
@ast
Bon-Kyoung Koo
@en
Bon-Kyoung Koo
@es
Bon-Kyoung Koo
@nl
type
label
Bon-Kyoung Koo
@ast
Bon-Kyoung Koo
@en
Bon-Kyoung Koo
@es
Bon-Kyoung Koo
@nl
prefLabel
Bon-Kyoung Koo
@ast
Bon-Kyoung Koo
@en
Bon-Kyoung Koo
@es
Bon-Kyoung Koo
@nl
P108
P1053
V-5219-2017
P106
P1153
8607696800
P21
P31
P496
0000-0002-4134-8033