about
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alphaCalmodulin binding to the Fas death domain. Regulation by Fas activationRgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrinsDe Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability SyndromeIntegrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src.Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cellsPND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insightsNuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.FERM control of FAK function: implications for cancer therapy.SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes.Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.FAK nuclear export signal sequences.A novel strong promoter of the groEx operon of symbiotic bacteria in Amoeba proteus.FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammationSyndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5-bisphosphate coordinately regulate protein kinase C activitySON haploinsufficiency causes impaired pre-mRNA splicing of CAKUT genes and heterogeneous renal phenotypesFAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expressionA Quantitative Method to Measure Low Levels of ROS in Nonphagocytic Cells by Using a Chemiluminescent Imaging SystemNuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 TranscriptionHypoxia induces cancer cell-specific chromatin interactions and increases MALAT1 expression in breast cancer cellsFAK Family Kinases in Vascular DiseasesTargeting focal adhesion kinase in cancer cells and the tumor microenvironment
P50
Q24294223-D5D4AD3E-357A-4574-9004-EF5D2F291C6CQ24299040-8AA7CB79-315E-410E-824D-6752919ED38CQ27302153-6E7C3BF6-442F-462C-9CFE-E9082289441CQ29147448-605E4C71-3970-4109-875C-9CA4C76EEA4AQ30476291-9C7A0991-BFD9-4456-8571-FAE750DCDD55Q30495320-ED0B0579-8294-4C8C-9A15-ADAA53889F6BQ33818123-AED4DBF7-DC60-4AE8-9F52-321C858323FAQ34103928-CE2FA99E-8586-4B80-AD59-D9ABE6E312F5Q34269196-CC422D86-EDE3-4080-AF76-E69069A29089Q34721988-D3A6B5BC-EABE-46E6-B378-058854EC1D2EQ35009792-52CC9872-80B8-468C-841F-DC97FDEF0D0CQ36062070-B141FD54-471E-4B11-A1FB-D1AA7A789D80Q37234240-F26C6E3E-31E6-4503-A859-86D7A1656411Q38785179-61840029-EFD6-47A9-90CB-552A717CE435Q40302237-A16F98A9-ABF1-4D08-AD32-151EAAEA5901Q41986858-3DB251F1-F529-4E44-A517-30A206BFB92BQ42693728-66D9E105-7B4C-4327-B826-FA25183701FFQ64268673-55ED8DA3-A221-4872-A85B-D75FEEB1F697Q74465611-C9746C4A-1A2E-4524-A0EF-E5C052E4A293Q90038226-3E013BAC-7BC0-4CBA-A0A3-E396848E1041Q91122890-D1B8852D-5337-4B0C-9CDE-91BF7AFE2C6DQ91725356-026FB1C7-E872-4314-B69B-7CB1E0EDDF96Q92084460-62E435E0-0CA9-45EA-AF51-800048AD8EACQ92546264-59081F49-63C4-487B-A34F-7D7E24302F63Q95825740-0870B649-6381-4738-80D7-07DEF29E8A00Q96231055-1C821FA8-6F3F-4096-850E-C539EB22E516
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ssang-Taek Lim
@ast
Ssang-Taek Lim
@en
Ssang-Taek Lim
@es
Ssang-Taek Lim
@nl
type
label
Ssang-Taek Lim
@ast
Ssang-Taek Lim
@en
Ssang-Taek Lim
@es
Ssang-Taek Lim
@nl
prefLabel
Ssang-Taek Lim
@ast
Ssang-Taek Lim
@en
Ssang-Taek Lim
@es
Ssang-Taek Lim
@nl
P106
P1153
57198489759
7404080738
P31
P496
0000-0003-0323-8607