Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
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Focal Adhesion Kinase: Insight into Molecular Roles and Functions in Hepatocellular CarcinomaFocal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices.Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells.Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line.Focal adhesion kinase maintains, but not increases the adhesion of dental pulp cells.Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview.Focal adhesion kinase signaling in unexpected places.pFAK-Y397 overexpression as both a prognostic and a predictive biomarker for patients with metastatic osteosarcoma.Interleukin-1β activates focal adhesion kinase and Src to induce matrix metalloproteinase-9 production and invasion of MCF-7 breast cancer cells.Somatic Mutations and Splicing Variants of Focal Adhesion Kinase in Non-Small Cell Lung Cancer.Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts.Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway.Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets.Focal Adhesion Kinase a Potential Therapeutic Target for Pancreatic Cancer and Malignant Pleural Mesothelioma.Berberine inhibits the chemotherapy-induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer.THSD7A expression in human cancer.Impact of PKCε downregulation on autophagy in glioblastoma cells.The Adhesion G-Protein-Coupled Receptor, GPR56/ADGRG1, Inhibits Cell-Extracellular Matrix Signaling to Prevent Metastatic Melanoma Growth.Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.Overexpression of epidermal growth factor receptor and its downstream effector, focal adhesion kinase, correlates with papillary thyroid carcinoma progression.The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.PathCORE-T: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia.Inhibiting focal adhesion kinase: A potential target for enhancing therapeutic efficacy in colorectal cancer therapyThe FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
P2860
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P2860
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
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2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@ast
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@en
type
label
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@ast
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@en
prefLabel
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@ast
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@en
P2093
P2860
P356
P1476
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
@en
P2093
Hyunho Yoon
James M Murphy
Joshua P Dehart
P2860
P304
P356
10.1369/0022155414561498
P577
2014-11-07T00:00:00Z