about
Guidelines for the use and interpretation of assays for monitoring autophagyCytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagyThe kinase domain of mitochondrial PINK1 faces the cytoplasmThe human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemiasPharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.Intrabody and Parkinson's diseaseDopamine-modified alpha-synuclein blocks chaperone-mediated autophagyNovel subcellular localization for α-synuclein: possible functional consequencesParkinson's disease: animal models and dopaminergic cell vulnerabilityAstrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neuronsInduction of mania by apomorphine in a depressed parkinsonian patientMotor blocks in Parkinson's diseaseEarly development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's diseaseVMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicityDJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidaseCHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonismBax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosisBax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's diseaseHuman stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypesParkinson's disease: mechanisms and modelsPINK1-dependent recruitment of Parkin to mitochondria in mitophagy.Selectively enhanced contextual fear conditioning in mice lacking the transcriptional regulator CCAAT/enhancer binding protein deltaNeuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's diseaseExpanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration.Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety.Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.Inflammation in ALS and SMA: sorting out the good from the evil.Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.Toxin-induced models of Parkinson's disease.D-β-hydroxybutyrate is protective in mouse models of Huntington's disease.Toxicity of the specific antimuscarinic agent methoctramine and other non-specific anticholinergic drugs in human neuroblastoma cell lines in vitro.The role of glial cells in Parkinson's disease.The last decade in Parkinson's disease research. Basic sciences.Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.Engineered modeling and the secrets of Parkinson's disease.Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS modelProtocol for the MPTP mouse model of Parkinson's disease.
P50
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P50
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Serge Przedborski
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P214
P214
P31
P7859
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