sameAs
Recent developments in yeast agingSir2-independent life span extension by calorie restriction in yeastIncreased life span due to calorie restriction in respiratory-deficient yeastExtension of chronological life span in yeast by decreased TOR pathway signalingThe TOR pathway comes of ageLessons on longevity from budding yeastmTOR is a key modulator of ageing and age-related diseaseReplicative and chronological aging in Saccharomyces cerevisiae.Histone H4 lysine 16 acetylation regulates cellular lifespanHealthy aging: The ultimate preventative medicineBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesThe MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegansTether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur proteinGenes determining yeast replicative life span in a long-lived genetic background.Elimination of replication block protein Fob1 extends the life span of yeast mother cells.Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and agingResveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeriaRegulation of yeast replicative life span by TOR and Sch9 in response to nutrientsSubstrate-specific activation of sirtuins by resveratrolUV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxinDietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.Proteasomal regulation of the hypoxic response modulates aging in C. elegansYODA: software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast.A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer.New functional and biophysical insights into the mitochondrial Rieske iron-sulfur protein from genetic suppressor analysis in C. elegans.The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.Measuring replicative life span in the budding yeastYeast as a model to understand the interaction between genotype and the response to calorie restrictionPreserving youth: does rapamycin deliver?The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress responseElevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiaeComposition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeastYeast replicative aging: a paradigm for defining conserved longevity interventions.Resveratrol and rapamycin: are they anti-aging drugs?A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespanSir2 and calorie restriction in yeast: a skeptical perspective.
P50
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P50
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American biologist
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biolojiste american
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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Matt Kaeberlein
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P214
P244
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0000 0004 0169 944X
P214
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lccn-no2013016610