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Q39777866-221E0CB3-2786-4B53-8C24-DD29AB37D755
Q39777866-221E0CB3-2786-4B53-8C24-DD29AB37D755
BestRank
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http://www.wikidata.org/entity/statement/Q39777866-221E0CB3-2786-4B53-8C24-DD29AB37D755
Critical role for a central part of Mdm2 in the ubiquitylation of p53.
P2860
Q39777866-221E0CB3-2786-4B53-8C24-DD29AB37D755
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39777866-221E0CB3-2786-4B53-8C24-DD29AB37D755
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wasDerivedFrom
55c0394b261d655202e18d05378872d24baa9493
P2860
The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo.