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about
sameAs
The RNA worlds in contextThe POT1-TPP1 telomere complex is a telomerase processivity factorHuman POT1 facilitates telomere elongation by telomerasePOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesHuman POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicingFinding the end: recruitment of telomerase to telomeresTelomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cellsGlobal expression changes resulting from loss of telomeric DNA in fission yeastDNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNAHow telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNAStructure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNAEssential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interactionA bulged stem tethers Est1p to telomerase RNA in budding yeast.Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13pSwitching human telomerase on and off with hPOT1 protein in vitroFunctional interaction between telomere protein TPP1 and telomeraseThe TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityStructure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active siteStructure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protectionTriple-helix structure in telomerase RNA contributes to catalysisMetal ion catalysis in the Tetrahymena ribozyme reactionIn vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequenceInhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.Academia and industry: Companies on campusEffects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation.In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron.The chemical repertoire of natural ribozymes.Evolution of Tetrahymena ribozyme mutants with increased structural stability.Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe.N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complexYeast telomerase is specialized for C/A-rich RNA templates.The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.Sharing publication-related data and materials: responsibilities of authorship in the life sciences.Sequence-specific and 3'-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit.Tetrahymena telomerase is active as a monomer.Beginning to understand the end of the chromosome.The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro.Yeast telomerase RNA: a flexible scaffold for protein subunits.Nurturing interdisciplinary research.
P50
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P50
subject
description
Ameerika Ühendriikide keemik
@et
American chemist
@en
American chemist
@en-ca
American chemist
@en-gb
Amerikaans biochemicus
@nl
US-amerikanischer Chemiker, Nobelpreisträger für Chemie
@de
americký chemik, nositel Nobelovy ceny za chemii
@cs
amerikansk biokemist
@sv
amerykański chemik
@pl
biochimico statunitense
@it
name
Chek Tomas
@uz
Thomas Cech
@ca
Thomas Cech
@cy
Thomas Cech
@da
Thomas Cech
@en
Thomas Cech
@en-ca
Thomas Cech
@en-gb
Thomas Cech
@eu
Thomas Cech
@fi
Thomas Cech
@ga
type
label
Chek Tomas
@uz
Thomas Cech
@ca
Thomas Cech
@cy
Thomas Cech
@da
Thomas Cech
@en
Thomas Cech
@en-ca
Thomas Cech
@en-gb
Thomas Cech
@eu
Thomas Cech
@fi
Thomas Cech
@ga
altLabel
Thomas Cech
@sv
Thomas R. Cech
@en
Thomas Robert Cech
@en
Thomas Robert Cech
@it
Томас Роберт Чек
@ru
prefLabel
Chek Tomas
@uz
Thomas Cech
@ca
Thomas Cech
@cy
Thomas Cech
@da
Thomas Cech
@en
Thomas Cech
@en-ca
Thomas Cech
@en-gb
Thomas Cech
@eu
Thomas Cech
@fi
Thomas Cech
@ga