Functional interaction between telomere protein TPP1 and telomerase
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentFinding the end: recruitment of telomerase to telomeresTelomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cellsMultiple facets of TPP1 in telomere maintenanceMolecular regulation of telomerase activity in agingThe shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulationThe TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityTelomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cellsThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisMultiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.Many disease-associated variants of hTERT retain high telomerase enzymatic activityIdentification of human TERT elements necessary for telomerase recruitment to telomeres.Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.Human telomerase: biogenesis, trafficking, recruitment, and activation.Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancerPot1 and telomere maintenance.Protection of Telomeres 1 is required for telomere integrity in the moss Physcomitrella patens.SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin.Insights into Cdc13 dependent telomere length regulation.Telomerase enzymatic component hTERT shortens long telomeres in human cells.Structural anatomy of telomere OB proteinsEvolution of CST function in telomere maintenance.InTERTpreting telomerase structure and functionA Cajal body-independent pathway for telomerase trafficking in mice.Stimulation of yeast telomerase activity by the ever shorter telomere 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2.Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteinsSingle-stranded DNA repeat synthesis by telomerasePOT1a and components of CST engage telomerase and regulate its activity in Arabidopsis.The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena.Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulationThe Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.POT1-TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism.Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance.
P2860
Q21263027-C31F8BC2-C9C8-48F9-9A0D-B125401BA889Q24293211-B00D1EAE-E61F-4B3D-B506-BD760770819FQ24606549-1BAF7FB8-09C2-4394-BCC5-808BE704DB20Q24617599-2B82DDBB-38FB-41BB-978E-9A3F67385866Q26859063-E9FC5E89-9382-4ACA-89B4-4D1DCC3952D4Q26861714-819B72DD-0F1F-4B5F-8EF6-A1814CBB8350Q28118567-495CFBB0-3666-46D3-993B-B9F4285DAE91Q28246056-9B3E20FE-F432-4AE2-9E73-9A52CB89B42FQ28278112-F1559635-AE02-4D5B-996D-FCAFEECC3A3DQ28565585-9D70B929-DC4F-40F3-8921-83E8E256EB2EQ28975759-BE98388F-B82E-4F38-890E-88CDC57A51D2Q30453497-90B5A67B-07E7-4702-A0BB-402365BA98E6Q30456846-DC59F2EA-8245-4DF1-BB14-F4FCF2C87FAEQ30459239-D6C050D2-777B-4547-95C2-C908009954E8Q30459426-DAD5EE49-3933-4D93-BD26-EA2B9363A2F0Q30459660-1EBA8B64-DFF3-47B0-80A2-3D24CAC00DA9Q33571895-D49D96BA-2638-4B94-9ABA-CDB314C3DDD4Q33584628-F955A9C4-585B-42AC-A2C2-067BAAE497E3Q33591938-877C899B-5BFB-42C5-80EE-676DF8A09279Q33701768-1A3F8011-BF02-43A2-AA7F-4193B152FEFCQ33727774-AD424570-5650-46FC-9FCC-8B4D282033C9Q33952974-4A58623F-7496-478A-9BB6-651B302691B3Q34032182-A8764410-6F7D-49F0-B5E4-8F0ABBBF922FQ34130588-554DAE7C-5FB8-4967-84D2-5A7AAB164EBBQ34146318-6EE8FFB0-4CCF-40CC-BB56-2447E8E80A67Q34154685-A6198B49-3081-4BED-A39A-64DEC05F8936Q35128162-B5E8F219-D1CE-4DF5-B15C-062EBE766811Q35170132-F2589520-5684-4D10-B730-8B92E038BA00Q35291572-7B33EA66-1F34-48A3-936B-7ABF336999C9Q35348694-A4AFAEE7-4EEB-4C76-9F1F-F5B30C635718Q35475132-EA726D9F-D1E9-4428-95C6-5BFBD1FEE6A3Q35651271-FCF97B45-DBEE-40C6-9C21-4FFB69720514Q35656533-5121AC53-BF3F-4A5F-B5B4-1896C36E7CBAQ35667156-B70FA252-4D46-4F88-AE4C-D57B3AFF0EA8Q35729880-44AFB695-89C4-420B-A1ED-1CC3D7D38B2FQ35822280-6B68F470-EBAD-4DA7-B5A6-7061E046AE54Q35921607-8B5AC547-ACED-4A01-94E9-1E6038DB76D6Q35926634-1AE54F48-E976-4D05-862D-994A0023073DQ36016284-648E6EAE-A85E-45D1-B8FA-838A8A63D589Q36140268-75B71C5D-9A6A-4E91-B7BB-E763E06BAABB
P2860
Functional interaction between telomere protein TPP1 and telomerase
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Functional interaction between telomere protein TPP1 and telomerase
@ast
Functional interaction between telomere protein TPP1 and telomerase
@en
Functional interaction between telomere protein TPP1 and telomerase
@nl
type
label
Functional interaction between telomere protein TPP1 and telomerase
@ast
Functional interaction between telomere protein TPP1 and telomerase
@en
Functional interaction between telomere protein TPP1 and telomerase
@nl
prefLabel
Functional interaction between telomere protein TPP1 and telomerase
@ast
Functional interaction between telomere protein TPP1 and telomerase
@en
Functional interaction between telomere protein TPP1 and telomerase
@nl
P2860
P50
P3181
P356
P1433
P1476
Functional interaction between telomere protein TPP1 and telomerase
@en
P2860
P304
P3181
P356
10.1101/GAD.1881810
P407
P577
2010-03-15T00:00:00Z