Hydroxysteroid 17-beta dehydrogenase 10

Hydroxysteroid 17-beta dehydrogenase 10

Item
http://www.wikidata.org/entity/Q21116211
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's diseaseA subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesisA non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex.The MRPP1/MRPP2 complex is a tRNA-maturation platform in human mitochondria.Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.Mutation or knock-down of 17β-hydroxysteroid dehydrogenase type 10 cause loss of MRPP1 and impaired processing of mitochondrial heavy strand transcripts.
P921

Hydroxysteroid 17-beta dehydrogenase 10

Item
http://www.wikidata.org/entity/Q21116211
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Hydroxysteroid 17-beta dehydrogenase 10
@en
Hydroxysteroid 17-beta dehydrogenase 10
@nl
type
label
Hydroxysteroid 17-beta dehydrogenase 10
@en
Hydroxysteroid 17-beta dehydrogenase 10
@nl
altLabel
1.1.1.178
@en
1.1.1.51
@en
17-beta-HSD 10
@en
17-beta-hydroxysteroid dehydrogenase 10
@en
3-hydroxy-2-methylbutyryl-CoA dehydrogenase
@en
3-hydroxyacyl-CoA dehydrogenase type II
@en
3-hydroxyacyl-CoA dehydrogenase type-2
@en
AB-binding alcohol dehydrogenase
@en
HSD17B10
@en
Mitochondrial RNase P protein 2
@en
prefLabel
Hydroxysteroid 17-beta dehydrogenase 10
@en
Hydroxysteroid 17-beta dehydrogenase 10
@nl
P31
P352
P361
P527
P591
P637
P638
P680
P681
P682
P702
P703
P705
P352
P637
P638
P31
P352
P361
P527
P591
P637
P638
P680
P681
P682
P702
P703
P705