A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
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TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephalyMechanistic and Structural Studies of Protein-Only RNase P Compared to Ribonucleoproteins Reveal the Two Faces of the Same Enzymatic ActivityThe Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological FunctionsModification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesMethylated nucleosides in tRNA and tRNA methyltransferasesCrystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substratetRNA biology in mitochondriaMitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All VertebratesRecessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies.Structure of the nuclease subunit of human mitochondrial RNase PEstrogen-mediated regulation of mitochondrial gene expression.Understanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'.A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs.The amyloid-β-SDR5C1(ABAD) interaction does not mediate a specific inhibition of mitochondrial RNase P.Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis.Genome-scale identification and characterization of moonlighting proteins.Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI).Mitochondrial energy failure in HSD10 disease is due to defective mtDNA transcript processingAuto-inhibitory Mechanism of the Human Mitochondrial RNase P Protein Complex.Mitochondrial transcript maturation and its disordersParkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10Diversity in mechanism and function of tRNA methyltransferases.Differential substrate recognition by isozymes of plant protein-only Ribonuclease PA novel HSD17B10 mutation impairing the activities of the mitochondrial RNase P complex causes X-linked intractable epilepsy and neurodevelopmental regressionPPR proteins shed a new light on RNase P biology.Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila.Factors That Shape Eukaryotic tRNAomes: Processing, Modification and Anticodon-Codon Use.Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease.Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA.The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs.Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expressionHuman mitochondrial nucleases.Substrate recognition and cleavage-site selection by a single-subunit protein-only RNase P.m1A Post-Transcriptional Modification in tRNAsRegulation of Mammalian Mitochondrial Gene Expression: Recent Advances.Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and FunctionMolecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex.Mechanistic features of the atypical tRNA m1G9 SPOUT methyltransferase, Trm10.RNase P enzymes: divergent scaffolds for a conserved biological reaction.Unexpected expansion of tRNA substrate recognition by the yeast m1G9 methyltransferase Trm10.
P2860
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P248
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P2860
A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
description
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Dezember 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/12/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/12/01)
@nl
наукова стаття, опублікована в грудні 2012
@uk
مقالة علمية (نشرت في ديسمبر 2012)
@ar
name
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@ast
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@en
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@nl
type
label
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@ast
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@en
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@nl
prefLabel
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@ast
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@en
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@nl
P2093
P2860
P921
P3181
P356
P1476
A subcomplex of human mitochon ...... mitochondrial tRNA biogenesis
@en
P2093
Andreas Taschner
Aurélie Buzet
Christa Nachbagauer
Johann Holzmann
P2860
P304
11583–11593
P3181
P356
10.1093/NAR/GKS910
P407
P577
2012-12-01T00:00:00Z