Human heparanase. Purification, characterization, cloning, and expression
about
Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequenceHeparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activityHeparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VIIStructural basis of heparan sulfate-specific degradation by heparinase IIICloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activityMechanisms of heparanase inhibitors in cancer therapy.Positive association of heparanase expression with tumor invasion and lymphatic metastasis in gastric carcinoma.Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.Unraveling the specificity of heparanase utilizing synthetic substrates.Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis.Role of heparanase on hepatic uptake of intestinal derived lipoprotein and fatty streak formation in mice.Isomalto oligosaccharide sulfate inhibits tumor growth and metastasis of hepatocellular carcinoma in nude mice.Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats.Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant.Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasisTumorigenic and adhesive properties of heparanase.Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cellsMolecular properties and involvement of heparanase in cancer metastasis and angiogenesis.Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis.Heparanase and coagulation-new insights.Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product.Expressions of heparanase and upstream stimulatory factor in hepatocellular carcinoma.Role of endothelial heparanase in delayed-type hypersensitivity.Expression and significance of heparanase and nm23-H1 in hepatocellular carcinomaMammalian heparanase: what is the message?An ELISA method for the detection and quantification of human heparanase.Antisense-mediated suppression of Heparanase gene inhibits melanoma cell invasion.Heparin-protein interactions.Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparinHeparanase expression in malignant salivary gland tumors inversely correlates with long-term survival.Post-transcriptional regulation of heparanase gene expression by a 3' AU-rich elementExpression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis.Cloning, expression, and characterization of an alternatively spliced variant of human heparanaseBrain metastases in melanoma: roles of neurotrophins.Heparanase as a molecular target of cancer chemotherapy.Microenvironmental and cellular consequences of altered blood flow in tumours.Heparanase mRNA expression and point mutation in hepatocellular carcinoma.Contribution of eIF-4E inhibition to the expression and activity of heparanase in human colon adenocarcinoma cell line: LS-174T.Heparanase localization during palatogenesis in mice.Heparanase: a target for drug discovery in cancer and inflammation.
P2860
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P2860
Human heparanase. Purification, characterization, cloning, and expression
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Human heparanase. Purification, characterization, cloning, and expression
@ast
Human heparanase. Purification, characterization, cloning, and expression
@en
Human heparanase. Purification, characterization, cloning, and expression
@en-gb
Human heparanase. Purification, characterization, cloning, and expression
@nl
type
label
Human heparanase. Purification, characterization, cloning, and expression
@ast
Human heparanase. Purification, characterization, cloning, and expression
@en
Human heparanase. Purification, characterization, cloning, and expression
@en-gb
Human heparanase. Purification, characterization, cloning, and expression
@nl
prefLabel
Human heparanase. Purification, characterization, cloning, and expression
@ast
Human heparanase. Purification, characterization, cloning, and expression
@en
Human heparanase. Purification, characterization, cloning, and expression
@en-gb
Human heparanase. Purification, characterization, cloning, and expression
@nl
P3181
P356
P1476
Human heparanase. Purification, characterization, cloning, and expression
@en
P2093
M Nakajima
M Toyoshima
P304
P3181
P356
10.1074/JBC.274.34.24153
P407
P577
1999-08-20T00:00:00Z