Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles
about
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositidesLayilin, a novel integral membrane protein, is a hyaluronan receptorFAK promotes recruitment of talin to nascent adhesions to control cell motilityActivation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundleThe integrin-actin connection, an eternal love affairStructural insight into the mechanisms of targeting and signaling of focal adhesion kinase.Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migrationDifferential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cellsTalin depletion reveals independence of initial cell spreading from integrin activation and traction.Localization of an integrin binding site to the C terminus of talin.How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism.Talin contains three similar vinculin-binding sites predicted to form an amphipathic helixDisruption of the talin gene arrests mouse development at the gastrulation stage.A novel alternative spliced chondrolectin isoform lacking the transmembrane domain is expressed during T cell maturation.Hyaluronan and layilin mediate loss of airway epithelial barrier function induced by cigarette smoke by decreasing E-cadherin.Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscleIntegrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration.Hyaluronan regulates cell behavior: a potential niche matrix for stem cellsTalin is required for integrin-mediated platelet function in hemostasis and thrombosis.Transcriptome profiling of human FoxP3+ regulatory T cellsTalin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.Structural and biophysical properties of the integrin-associated cytoskeletal protein talin.Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.Mechanisms of talin-dependent integrin signaling and crosstalkTranscriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.Further characterization of the interaction between the cytoskeletal proteins talin and vinculin.The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.Layilin is critical for mediating hyaluronan 35kDa-induced intestinal epithelial tight junction protein ZO-1 in vitro and in vivo.Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain.Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma.Phospholipid binding of synthetic talin peptides provides evidence for an intrinsic membrane anchor of talin.
P2860
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P2860
Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Layilin, a novel talin-binding ...... localized in membrane ruffles
@ast
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en-gb
Layilin, a novel talin-binding ...... localized in membrane ruffles
@nl
type
label
Layilin, a novel talin-binding ...... localized in membrane ruffles
@ast
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en-gb
Layilin, a novel talin-binding ...... localized in membrane ruffles
@nl
prefLabel
Layilin, a novel talin-binding ...... localized in membrane ruffles
@ast
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en-gb
Layilin, a novel talin-binding ...... localized in membrane ruffles
@nl
P2860
P356
P1476
Layilin, a novel talin-binding ...... localized in membrane ruffles
@en
P2093
M L Borowsky
P2860
P304
P356
10.1083/JCB.143.2.429
P407
P577
1998-10-19T00:00:00Z