Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation
about
The Pafah1b complex interacts with the reelin receptor VLDLRSimilarities and differences in structure, expression, and functions of VLDLR and ApoER2Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasisQuantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregationA secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signalingReelin expression and glycosylation patterns are altered in Alzheimer's diseaseSynergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brainGenome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's diseaseReelin and apolipoprotein E receptor 2 in the embryonic and mature brain: effects of an evolutionary change in the apoER2 geneReceptor clustering is involved in Reelin signalingReelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deploymentThe involvement of Reelin in neurodevelopmental disorders.Regulation of protein tyrosine kinase signaling by substrate degradation during brain developmentSialidase-like Asp-boxes: sequence-similar structures within different protein foldsA neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteinsThe Reelin signaling pathway promotes dendritic spine development in hippocampal neuronsThe N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neuronsLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseReelin signaling antagonizes beta-amyloid at the synapseMutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humansReduction of Crk and CrkL expression blocks reelin-induced dendritogenesisInteraction of reelin with amyloid precursor protein promotes neurite outgrowthThrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migrationStructure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptorsReelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibodyReelin secretion from glutamatergic neurons in culture is independent from neurotransmitter regulationColocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortexExpression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cellsStructure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomographySrc family kinases directly regulate JIP1 module dynamics and activationApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of ReelinCanonical and Non-canonical Reelin SignalingNew Insights into Reelin-Mediated Signaling PathwaysStructural Insights into Reelin Function: Present and FutureReelin Proteolysis Affects Signaling Related to Normal Synapse Function and NeurodegenerationRELN Mutations in Autism Spectrum DisorderReelin Signaling in the Migration of Ventral Brain Stem and Spinal Cord NeuronsEpigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric DisordersLow Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell FunctionConsensus paper: pathological role of the cerebellum in autism
P2860
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P2860
Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@ast
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en-gb
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@nl
type
label
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@ast
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en-gb
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@nl
prefLabel
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@ast
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en-gb
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@nl
P2093
P921
P3181
P1433
P1476
Direct binding of Reelin to VL ...... modulates tau phosphorylation
@en
P2093
A Goffinet
B W Howell
J A Cooper
M Trommsdorff
T Hiesberger
P3181
P356
10.1016/S0896-6273(00)80861-2
P407
P577
1999-10-01T00:00:00Z