A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling - Wikidata - thesis-toulmin - TriplyDB

A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling

A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling

http://www.wikidata.org/entity/Q24537683

about

The generation and function of soluble apoE receptors in the CNS The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2 Receptor clustering is involved in Reelin signaling Regulation of protein tyrosine kinase signaling by substrate degradation during brain development A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors Structural Insights into Reelin Function: Present and Future The neurogenetics of alternative splicing Reelin and apoE actions on signal transduction, synaptic function and memory formation The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning Cullin 5 regulates cortical layering by modulating the speed and duration of Dab1-dependent neuronal migration Predicting functional alternative splicing by measuring RNA selection pressure from multigenome alignments Insights into synaptic function from mouse models of human cognitive disorders.Both the phosphoinositide and receptor binding activities of Dab1 are required for Reelin-stimulated Dab1 tyrosine phosphorylation.Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant.Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway.New light on a long-known protein family.Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family.A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol.The β-amyloid peptide compromises Reelin signaling in Alzheimer's disease.Clusterin is a ligand for apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and signals via the Reelin-signaling pathway.Signaling by the extracellular matrix protein Reelin promotes granulosa cell proliferation in the chicken follicle Isoform-specific binding of selenoprotein P to the β-propeller domain of apolipoprotein E receptor 2 mediates selenium supply.Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses.How does Reelin signaling regulate the neuronal cytoskeleton during migration?The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Differential functions of ApoER2 and very low density lipoprotein receptor in Reelin signaling depend on differential sorting of the receptors.Reelin in Alzheimer's Disease, Increased Levels but Impaired Signaling: When More is Less.Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts.ApoE isoform-dependent changes in hippocampal synaptic function Extracellular matrices of the avian ovarian follicle. Molecular characterization of chicken perlecan.Binding of low density lipoprotein to platelet apolipoprotein E receptor 2' results in phosphorylation of p38MAPK.Molecular cloning, expression and association study with reproductive traits of the duck LRP8 gene.

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P2860

A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling

http://www.wikidata.org/entity/Q24537683

description

2002 nî lūn-bûn

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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@ast

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@en

A secreted soluble form of Apo ...... and inhibits Reelin signaling

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type

label

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@ast

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@en

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@nl

prefLabel

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@ast

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@en

A secreted soluble form of Apo ...... and inhibits Reelin signaling

@nl

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The EMBO Journal

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A secreted soluble form of Apo ...... and inhibits Reelin signaling

@en

P2093

Christian Brandes

http://www.w3.org/2001/XMLSchema#string

Christoph Hauser

http://www.w3.org/2001/XMLSchema#string

Daniela Fasching

http://www.w3.org/2001/XMLSchema#string

Stefanie Koch

http://www.w3.org/2001/XMLSchema#string

Tarek M Bajari

http://www.w3.org/2001/XMLSchema#string

Vera Strasser

http://www.w3.org/2001/XMLSchema#string

Wolfgang J Schneider

http://www.w3.org/2001/XMLSchema#string

P2860

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

Reelin is a ligand for lipoprotein receptors

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

Localization of apolipoprotein E receptor 2 to caveolae in the plasma membrane

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

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scholarly article

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1221529

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10.1093/EMBOJ/CDF599

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22

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21

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2002-11-01T00:00:00Z

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11041179

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12426372

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137191

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